Overview
5-Bromovaleric acid is a brominated carboxylic acid with a five-carbon chain, widely used as a versatile intermediate in organic synthesis. Its molecular structure includes a reactive bromine atom, making it valuable for nucleophilic substitution reactions. This compound is particularly significant in the pharmaceutical industry, where it serves as a building block for active pharmaceutical ingredients (APIs) and other fine chemicals. Due to its reactivity, it is often utilized in the production of agrochemicals and specialty chemicals.
Physical and Chemical Properties
5-Bromovaleric acid typically appears as a clear to pale yellow liquid with a density of approximately 1.48 g/cm³. It is soluble in common organic solvents like ethanol and ether but has limited solubility in water. The presence of the bromine atom enhances its reactivity, making it a useful intermediate for alkylation and other substitution reactions. Its molecular weight is 181.03 g/mol, and it should be handled carefully due to its corrosive and irritant properties.
Main Applications
The primary use of 5-bromovaleric acid is in organic synthesis, where it acts as an intermediate for pharmaceuticals, agrochemicals, and specialty chemicals. It is often employed in the synthesis of valproic acid derivatives and other therapeutic compounds. In agrochemicals, it serves as a precursor for herbicides and pesticides. Its versatility also extends to the production of fragrances, dyes, and other fine chemicals, making it a valuable compound in industrial chemistry.
Safety and Storage
5-Bromovaleric acid is corrosive and can cause skin and eye irritation. Proper personal protective equipment (PPE), including gloves and goggles, should be worn when handling this chemical. Avoid inhalation and direct contact. Store the compound in a cool, dry, well-ventilated area, away from incompatible materials such as strong oxidizers and bases. Ensure containers are tightly sealed to prevent moisture absorption and degradation.
B2B Procurement Guide
When procuring 5-bromovaleric acid, verify the CAS number (2067-33-6) and request a certificate of analysis (CoA) to ensure purity and quality. Reputable suppliers should provide detailed specifications and safety data sheets (SDS). Consider purchasing in bulk for cost savings, but ensure proper storage conditions are maintained. Prices typically range from $50 to $200 per kilogram, depending on purity and order volume. Always prioritize suppliers with a proven track record in chemical distribution.
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