Overview
4',7-Dimethoxy-5-hydroxyflavone is a naturally occurring flavonoid derivative, characterized by its distinct molecular structure featuring methoxy and hydroxyl functional groups. Flavonoids like this compound are widely studied for their potential biological activities, including antioxidant, anti-inflammatory, and anticancer properties. This compound is primarily utilized in academic and industrial research settings, where it serves as a reference standard or a building block for synthesizing more complex molecules. Its applications extend to pharmaceutical development and nutraceutical formulations, where flavonoids are valued for their health benefits.
Physical and Chemical Properties
4',7-Dimethoxy-5-hydroxyflavone typically presents as a yellow to pale brown crystalline powder. It has a molecular weight of 298.29 g/mol and a melting point ranging between 180-185°C, which is characteristic of many flavonoid compounds. The compound is soluble in common organic solvents such as dimethyl sulfoxide (DMSO) and methanol but exhibits limited solubility in water. This solubility profile makes it suitable for laboratory use in organic synthesis and biochemical assays. Its stability under standard storage conditions (cool, dry, and protected from light) ensures long-term usability.
Main Applications
In pharmaceutical research, 4',7-Dimethoxy-5-hydroxyflavone is investigated for its potential role in modulating cellular pathways, particularly those related to oxidative stress and inflammation. Its flavonoid backbone makes it a candidate for developing novel therapeutics. Beyond pharmaceuticals, the compound is used in nutraceuticals and dietary supplements, leveraging its antioxidant properties. Researchers also employ it as a standard in chromatographic analyses to identify or quantify similar flavonoids in plant extracts or biological samples.
Safety and Storage
While 4',7-Dimethoxy-5-hydroxyflavone is not classified as highly hazardous, standard laboratory precautions should be followed. Avoid inhalation of dust and direct skin contact by using gloves, goggles, and lab coats. In case of exposure, rinse thoroughly with water and seek medical advice if irritation persists. For storage, keep the compound in a tightly sealed container under cool, dry conditions, away from light and moisture. These measures prevent degradation and maintain the compound's integrity over time. Label containers clearly with hazard information and handling instructions.
B2B Procurement Guide
When procuring 4',7-Dimethoxy-5-hydroxyflavone, prioritize suppliers with verified credentials and a track record of delivering high-purity chemicals. Request certificates of analysis (CoA) to confirm purity, typically assessed via HPLC or GC methods. Consider batch-to-batch consistency and regulatory compliance, especially if the compound is intended for pharmaceutical use. Bulk purchases may offer cost advantages, but ensure the supplier can meet your volume requirements without compromising quality. Lead times and shipping conditions (e.g., temperature control) should also be factored into procurement decisions.
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