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4-tert-Butylphenol

Updated: 2026-07-15

Overview

4-tert-Butylphenol (4-TBP) is a derivative of phenol, characterized by a tert-butyl group at the para position. It is a versatile intermediate in organic synthesis, valued for its stabilizing and antioxidative properties. Industrially, 4-TBP is produced by alkylating phenol with isobutylene. Its applications span adhesives, coatings, and specialty chemicals, driven by its ability to enhance product durability and performance.

Physical and Chemical Properties

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4-TBP exhibits moderate solubility in water but dissolves readily in organic solvents like ethanol and ether. Its crystalline form and phenolic odor are distinctive physical traits. Chemically, it reacts with bases to form salts and undergoes electrophilic substitution at the ortho/para positions. Its stability under normal conditions makes it suitable for long-term storage, though it degrades under strong oxidizers.

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Main Applications

In the polymer industry, 4-TBP serves as a monomer for phenolic resins and a stabilizer for PVC. It also functions as an antioxidant in lubricants and fuels. Other uses include fragrance fixation in perfumes and as a precursor for UV absorbers. Its role in synthesizing agrochemicals and pharmaceuticals further underscores its industrial importance.

Safety and Storage

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4-TBP requires careful handling due to its irritant properties. Use gloves, goggles, and respirators to prevent exposure. Spills should be contained with inert absorbents. Store in sealed containers at temperatures below 30°C, away from incompatible substances like strong acids. Proper ventilation is critical to avoid vapor accumulation.

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B2B Procurement Guide

Buyers should prioritize suppliers with proven track records in chemical manufacturing. Key criteria include batch consistency, SDS availability, and compliance with regional regulations (e.g., REACH, OSHA). Bulk purchases typically offer cost advantages. Negotiate terms for logistics (e.g., hazardous material transport) and confirm lead times to align with production schedules.

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