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4-Pregnene-20

Updated: 2026-07-24

Overview

Pregn-4-ene-20 is a steroid compound with a molecular formula of C21H32O. It is primarily used in pharmaceutical and biochemical research as an intermediate in the synthesis of steroid hormones. The compound features a pregnane skeleton, making it valuable for studying hormone-related pathways and developing therapeutic agents. Due to its structural similarity to naturally occurring steroids, Pregn-4-ene-20 is often utilized in laboratories to investigate metabolic processes and hormone interactions. Its applications extend to the production of synthetic hormones and other bioactive molecules.

Physical and Chemical Properties

Pregn-4-ene-20 typically appears as a white to off-white crystalline powder. It has a melting point of approximately 150-155°C and is soluble in organic solvents like ethanol and methanol, though it is insoluble in water. The compound's molecular weight is 300.48 g/mol. The steroid backbone of Pregn-4-ene-20 provides stability and reactivity, making it suitable for various chemical modifications. Its solubility profile allows for easy handling in laboratory settings, particularly in organic synthesis and analytical procedures.

Main Applications

Pregn-4-ene-20 is widely used in pharmaceutical research, particularly in the development and study of steroid hormones. It serves as a key intermediate in the synthesis of corticosteroids, progestogens, and other hormone derivatives. In biochemical studies, the compound is employed to explore hormone-receptor interactions and metabolic pathways. Its role in producing bioactive molecules makes it indispensable for laboratories focused on endocrinology and drug development.

Safety and Storage

When handling Pregn-4-ene-20, it is essential to use appropriate personal protective equipment (PPE), including gloves and safety goggles, to prevent skin contact or inhalation. The compound should be stored in a cool, dry place, protected from light and moisture to maintain its stability. Proper disposal methods should be followed to minimize environmental impact. Always refer to the material safety data sheet (MSDS) for specific handling and storage guidelines.

B2B Procurement Guide

When procuring Pregn-4-ene-20, buyers should prioritize suppliers with verified credentials and a track record of providing high-purity compounds. It is advisable to request certificates of analysis (CoA) to confirm the product's purity and composition. Prices vary depending on the quantity and supplier, so obtaining multiple quotes is recommended. Bulk purchases may offer cost advantages, but storage conditions must be ensured to preserve the compound's integrity.

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