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4-Phenoxybenzaldehyde

Updated: 2026-08-02

Overview

4-Phenoxybenzaldehyde is an organic compound belonging to the class of aromatic aldehydes. It is widely recognized for its role as a key intermediate in the synthesis of various pharmaceuticals, agrochemicals, and specialty chemicals. The compound features a benzaldehyde core substituted with a phenoxy group at the para position, which influences its reactivity and applications. Industrially, 4-Phenoxybenzaldehyde is valued for its versatility in chemical reactions, including condensation and oxidation processes. Its stable yet reactive nature makes it a preferred choice for researchers and manufacturers aiming to develop complex organic molecules with specific functional properties.

Physical and Chemical Properties

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4-Phenoxybenzaldehyde appears as a white to pale yellow crystalline powder with a characteristic aromatic odor. It has a molecular weight of 198.22 g/mol and a melting point range of 45-48°C. The compound is soluble in common organic solvents such as ethanol, ether, and acetone but exhibits limited solubility in water. Chemically, it behaves as a typical aromatic aldehyde, participating in reactions like nucleophilic addition and oxidation. The phenoxy group enhances its electron density, making it slightly more reactive than unsubstituted benzaldehyde. These properties are crucial for its applications in synthetic chemistry.

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Main Applications

The primary use of 4-Phenoxybenzaldehyde is as an intermediate in the pharmaceutical industry, where it contributes to the synthesis of active pharmaceutical ingredients (APIs). It is also employed in agrochemical production, particularly in creating pesticides and herbicides with enhanced efficacy. Additionally, the compound finds applications in the fragrance industry, where its aromatic properties are leveraged to develop complex scent profiles. Its role in specialty chemical synthesis further extends to dyes, coatings, and other high-value products requiring precise molecular structures.

Safety and Storage

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Handling 4-Phenoxybenzaldehyde requires adherence to standard safety protocols to minimize exposure risks. The compound may cause irritation upon contact with skin, eyes, or respiratory systems. Proper personal protective equipment (PPE), including gloves and goggles, is recommended during use. Storage should be in a cool, dry environment, protected from light and moisture to prevent degradation. Containers must be tightly sealed and labeled clearly to avoid confusion with other chemicals. In case of spills, neutralization with appropriate agents and disposal according to local regulations is advised.

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B2B Procurement Guide

When procuring 4-Phenoxybenzaldehyde, businesses should prioritize suppliers with verified credentials and a track record of delivering high-purity chemicals. Key considerations include CAS number verification, batch purity certificates, and compliance with international safety standards. Bulk purchases often attract discounts, but it's essential to balance cost with storage capabilities to avoid material degradation. Requesting samples for quality testing before large-scale orders can mitigate risks. Additionally, inquire about packaging options to ensure stability during transit and storage.

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