Overview
4-Methoxycinnamic acid is a derivative of cinnamic acid, featuring a methoxy group at the para position of the phenyl ring. It is commonly used in various industries due to its unique chemical properties. The compound is synthesized through the Perkin reaction or other organic synthesis methods. Its applications range from pharmaceuticals to cosmetics, where it serves as an active ingredient or additive. This compound is known for its ability to absorb ultraviolet (UV) light, making it valuable in sunscreens and other UV-protective formulations. Additionally, its antioxidant properties contribute to its use in preserving food and cosmetic products. The demand for 4-methoxycinnamic acid continues to grow, particularly in markets focusing on natural and synthetic additives.
Physical and Chemical Properties
4-Methoxycinnamic acid is a white to off-white crystalline solid with a melting point range of 168-172 °C. It is sparingly soluble in water but dissolves well in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO). The compound exhibits strong UV absorption, particularly in the UVA and UVB ranges, which is why it is often incorporated into sunscreens. The presence of the methoxy group enhances its stability and reactivity compared to unsubstituted cinnamic acid. This modification also influences its solubility and interaction with other chemicals, making it versatile for various formulations. Its molecular weight of 178.18 g/mol and specific functional groups contribute to its role in organic synthesis and industrial applications.
Main Applications
In the pharmaceutical industry, 4-methoxycinnamic acid is used as an intermediate in the synthesis of drugs, particularly those with anti-inflammatory or antimicrobial properties. Its ability to inhibit certain enzymes makes it valuable in medicinal chemistry. Additionally, it is explored for its potential in treating skin conditions due to its UV-protective effects. The cosmetic industry leverages this compound in sunscreens, anti-aging creams, and other skincare products. Its UV-absorbing and antioxidant properties help protect the skin from damage caused by free radicals and sunlight. In the food and flavor industry, it is used as a flavoring agent and preservative, though its applications here are more limited compared to other sectors.
Safety and Storage
4-Methoxycinnamic acid should be handled with care to avoid inhalation, ingestion, or skin contact. Personal protective equipment (PPE) such as gloves, goggles, and lab coats are recommended when working with this chemical. In case of exposure, rinse affected areas with plenty of water and seek medical attention if necessary. Proper storage involves keeping the compound in a tightly sealed container in a cool, dry place away from direct sunlight and moisture. It should not be stored near strong oxidizing agents or incompatible materials. Shelf life is generally long if stored correctly, but it is advisable to check for degradation or discoloration before use.
B2B Procurement Guide
When procuring 4-methoxycinnamic acid, it is essential to verify the CAS number (943-89-5) to ensure the correct compound is being purchased. Purity levels should be confirmed through certificates of analysis (CoA) provided by the supplier. Common purity grades range from 98% to 99.5%, depending on the application requirements. Suppliers should be evaluated based on their reputation, compliance with regulatory standards, and ability to provide consistent quality. Bulk purchases may offer cost savings, but it is crucial to assess storage capabilities to prevent degradation. Prices vary based on purity, quantity, and supplier, with a typical range of $50-$100 per kilogram. Request samples for testing before large-scale procurement to ensure suitability for intended use.
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