Overview
4-Iodobenzamide is an organic compound widely used in pharmaceutical research and industrial applications. Its molecular structure includes an iodine atom, which makes it valuable for various synthetic processes. The compound is typically synthesized through the reaction of 4-iodobenzoic acid with ammonia or its derivatives. Due to its stability and reactivity, 4-Iodobenzamide serves as a key intermediate in the development of new drugs and other organic compounds. It is particularly useful in cross-coupling reactions, which are essential in medicinal chemistry.
Physical and Chemical Properties
4-Iodobenzamide is a white to off-white crystalline powder with a molecular weight of 247.03 g/mol. It has a melting point of approximately 180-185°C, which makes it stable under typical laboratory conditions. The compound is soluble in organic solvents such as DMSO and methanol but only slightly soluble in water. Its chemical stability and solubility profile make it suitable for various organic synthesis applications. The presence of the iodine atom in its structure allows for further functionalization, which is crucial in pharmaceutical development.
Main Applications
The primary use of 4-Iodobenzamide is as an intermediate in pharmaceutical synthesis. It is often employed in the production of active pharmaceutical ingredients (APIs) and other specialized chemicals. The compound's reactivity makes it valuable in cross-coupling reactions, which are pivotal in creating complex molecular structures. In addition to pharmaceuticals, 4-Iodobenzamide is used in academic and industrial research for developing new organic compounds. Its applications extend to materials science, where it serves as a building block for advanced materials.
Safety and Storage
4-Iodobenzamide should be handled with care to avoid exposure. Proper personal protective equipment (PPE), including gloves and goggles, is recommended. The compound should be stored in a cool, dry place, away from light and moisture to maintain its stability. In case of accidental exposure, immediate medical attention is advised. Safety data sheets (SDS) should be consulted for detailed handling and disposal guidelines. Proper ventilation is essential when working with this compound in laboratory settings.
B2B Procurement Guide
When procuring 4-Iodobenzamide, it is essential to verify the supplier's credentials and ensure they provide a certificate of analysis (COA). The compound should be packaged in airtight containers to prevent degradation during transit. Bulk purchases may offer cost advantages, but storage conditions must be optimized to maintain quality. Buyers should also consider the compound's shelf life and plan procurement accordingly to avoid wastage. Reliable suppliers with a track record in chemical distribution are preferred.
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