Overview
4-Hydroxybenzhydrazide is a hydrazide derivative of 4-hydroxybenzoic acid. It is primarily used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. The compound is known for its reactivity, making it valuable in organic synthesis, particularly in the formation of heterocyclic compounds. Its applications extend to the development of biologically active molecules, including antimicrobial and antifungal agents. Due to its functional groups, it serves as a versatile building block in medicinal chemistry.
Physical and Chemical Properties
4-Hydroxybenzhydrazide appears as a white to off-white crystalline powder with a melting point range of 165-170°C. It is soluble in water and common organic solvents such as ethanol and methanol, which facilitates its use in various chemical reactions. The compound's molecular weight is 152.15 g/mol, and its structure includes both a hydroxyl group and a hydrazide functional group. These features contribute to its reactivity, particularly in condensation and cyclization reactions.
Main Applications
The primary use of 4-Hydroxybenzhydrazide is as an intermediate in the pharmaceutical industry. It is involved in the synthesis of drugs targeting infections and metabolic disorders. Additionally, it finds applications in agrochemicals for developing pesticides and herbicides. In organic synthesis, it is employed to create heterocyclic compounds, which are crucial in medicinal chemistry. Its versatility also makes it useful in research laboratories for developing new chemical entities.
Safety and Storage
Handling 4-Hydroxybenzhydrazide requires precautions to avoid exposure. Protective equipment such as gloves, goggles, and lab coats should be worn. Inhalation or skin contact can cause irritation, and ingestion should be avoided. Storage conditions include keeping the compound in a cool, dry place, away from direct sunlight and moisture. Properly sealed containers are essential to maintain its stability and prevent degradation.
B2B Procurement Guide
When procuring 4-Hydroxybenzhydrazide, buyers should verify the supplier's credibility and request a Certificate of Analysis (COA) to ensure purity and quality. Bulk purchases may offer cost advantages, but storage capacity should be considered. It is advisable to compare prices from multiple suppliers, as rates can vary based on purity and quantity. Ensure that the packaging is suitable for safe transportation and long-term storage.
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