Overview
4-Hydroxybenzaldehyde (4-HBA) is an organic compound belonging to the class of aromatic aldehydes. It is characterized by a hydroxyl group (-OH) attached to the benzene ring at the para position relative to the aldehyde group (-CHO). This structure makes it a versatile intermediate in organic synthesis. 4-HBA is naturally occurring and can be found in some plants, but it is primarily produced synthetically for industrial applications. Its derivatives are widely used in pharmaceuticals, fragrances, and agrochemicals due to their reactivity and functional groups.
Physical and Chemical Properties
4-Hydroxybenzaldehyde is a white to pale yellow crystalline powder with a faint aromatic odor. It has a melting point of 115-117°C and a boiling point of 246°C. The compound is soluble in water, ethanol, and ether, making it suitable for various solvent-based applications. Chemically, 4-HBA is reactive due to the presence of both aldehyde and hydroxyl functional groups. It can undergo reactions such as oxidation, reduction, and condensation, making it valuable for synthesizing more complex molecules. Its stability under normal conditions allows for easy handling and storage.
Main Applications
4-Hydroxybenzaldehyde is a key intermediate in the pharmaceutical industry, used in the synthesis of drugs such as antimicrobials and antihypertensives. Its derivatives are also employed in the production of fragrances and flavors, contributing to floral and almond-like notes. In agrochemicals, 4-HBA is used to manufacture herbicides and pesticides. Additionally, it serves as a building block in the synthesis of dyes and polymers. Its versatility and reactivity make it indispensable in fine chemical production.
Safety and Storage
4-Hydroxybenzaldehyde should be handled with care to avoid skin and eye irritation. Proper personal protective equipment (PPE), including gloves and goggles, is recommended. In case of contact, rinse immediately with water. Storage conditions are critical to maintaining the compound's stability. It should be kept in a cool, dry place, away from direct sunlight and moisture. Sealed containers are preferred to prevent degradation and contamination.
B2B Procurement Guide
When procuring 4-Hydroxybenzaldehyde, buyers should prioritize purity (typically 98-99%) and verify supplier certifications. Packaging options include 25 kg drums or custom quantities, depending on the buyer's needs. Price ranges from approximately $20 to $50 per kg, influenced by purity, quantity, and supplier reputation. Bulk purchases may offer cost advantages. Always request samples and conduct quality tests before large-scale procurement.
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