Overview
4-Hydroxy-7-methoxyquinoline is a quinoline derivative characterized by a hydroxyl group at the 4-position and a methoxy group at the 7-position of the quinoline ring. It serves as a versatile intermediate in pharmaceutical synthesis and organic chemistry research. This compound is particularly valued for its role in the development of bioactive molecules, including potential drug candidates. Its structural features make it a useful building block for more complex chemical entities.
Physical and Chemical Properties
The compound typically appears as an off-white to light yellow crystalline powder with a melting point range of approximately 200-205°C. It is soluble in common organic solvents such as ethanol and dimethyl sulfoxide (DMSO), but only slightly soluble in water. The presence of both hydroxyl and methoxy groups on the quinoline ring contributes to its chemical reactivity, making it suitable for various synthetic transformations. These functional groups allow for further derivatization through reactions like alkylation, acylation, or condensation.
Main Applications
4-Hydroxy-7-methoxyquinoline finds primary use as a pharmaceutical intermediate in the synthesis of more complex drug molecules. Its quinoline core structure is common in many biologically active compounds, making it valuable for medicinal chemistry research. Additionally, this compound serves as a research chemical in academic and industrial laboratories studying quinoline chemistry. It may also find application in the development of specialty chemicals and materials where the quinoline scaffold is required.
Safety and Storage
As with many chemical compounds, proper handling procedures should be followed when working with 4-hydroxy-7-methoxyquinoline. Standard laboratory safety practices including the use of gloves, protective eyewear, and adequate ventilation are recommended. The compound should be stored in a cool, dry environment away from direct light and moisture. Properly sealed containers are essential to maintain product integrity and prevent degradation over time.
B2B Procurement Guide
When sourcing 4-hydroxy-7-methoxyquinoline for industrial or research purposes, buyers should prioritize suppliers with demonstrated expertise in fine chemicals. Key considerations include certificate of analysis review, purity verification, and supplier reliability. For bulk procurement, it's advisable to request samples for quality assessment before large-scale orders. Buyers should also confirm that the supplier meets relevant regulatory requirements for chemical production and distribution.
Related Manufacturers
- 主营：杜仲素、对位酯、丙烯酸酯、4羟基67二甲氧基喹啉、二氧化硫脲、乙基麦芽酚、饲料添加剂、油酸基硬脂酸、二苯基硅二醇
- 主营：三硫代碳酸钠、聚乙烯亚胺、三乙二醇二异辛酸酯、红色素-16、L-丙交酯、石油酯-T50、巯基苯并噻唑钠、乙交酯、多元醇苯甲酸酯、热压敏染料、光稳定剂、高分子降解材料
- 主营：化学试剂、氯金酸、卡尔费休、羟基、乙醇、异丙醇、药用辅料、依地酸钙钠、碳酸钠、盐酸氨丁三醇、龙胆酸、枸橼酸钠、甲醇、氢氧化钠、钴锰催化剂、硫酸锰、乙腈、色谱试剂、助剂、指示剂、醋酸锰、醋酸钴、氨丁三醇、尿素、硼酸
- 主营：硼酸酐、阻聚剂、己二酸、6-氯嘌呤、氯化锂、发泡剂、乙二醇、醋酸铜、硅酸钠、正癸醇、新癸酸、环烷油、腰果酚、十二醇、酒石酸、碳酸锂、三甘醇、油菜酸、二甘醇、碳酸钾、甲酸钠、硅酸镁、棕榈油、微晶石蜡、磷酸一铵
- 主营：硫酸烟酰苯胺、甲基磺酸铋、异硬脂酸、TS-1钛硅分子筛、2-氯丙酰氯、油酸咪唑啉、苯基膦酸、单宁酸、抗氧剂、中间体、离子液体
- 主营：化工中间体、食品添加剂、化工原料
- 主营：聚乙烯胺、化学试剂、分析试剂、羟基、通用试剂、生化试剂
- 主营：苯甲醛、酰亚胺、苯磺酸、cas-50-63-5、异丙基、氨基丙基、试剂医药、化学醋酸、化学试剂、甲基硅基、盐酸羟胺、苯并三唑、苄基丙酮、试剂化工、丙烯酰氯、甲基乙炔、氮杂苯并、二叔丁酯、磷酸二苯酯、化学碳酸钾、二酸二乙酯、酸二异丙酯、二咪唑羰基、中间体化工、医药中间体
- 主营：4羟基7甲氧基喹啉、氨基丁酸、漆酶、维生素
- 主营：三癸基铝、甲氧苯基、磺胺曲沙唑、17746-77-9、625392-06-5、1423716-55-5、1547041-34-8、8-二羟基萘、甲氧基苯甲酸、4-氯嘧啶盐酸盐、三十二烷基铝
- 主营：碘甲苯、阻燃剂、碘丙烷、3.4-二氟、2-丙二醇、cas627-30-5、cas766-85-8、1-碘辛烷、1-碘己烷、cas107-05-1、cas585-79-5、cas150-19-6、cas831-82-3、碘丁烷、溴苯胺、碘癸烷、苯乙酮、碘苯胺、碘乙烷、苯甲酸、溴苯酚、苯甲腈、ab黑白料、苯甲酰胺、聚碳酸酯
- 主营：网站建设、企业官网设计、网站搭建
- 主营：甲氨基、防老剂、共聚物、2349-67-9、82692-96-4、37052-78-1、4-三羧酸、6-氯烟酸、l-丙交酯、l-胱氨酸、二聚体、乙交酯、聚乳酸、三氨基、苯乙酮、磺丙基、丙烯酸、羟甲基、胡椒酸、羟乙基、防黄剂、氯甲基、二氨基、edta二钠、2苯并异
- 主营：二乙基、黄棕6gd、异戊酯、溴喹啉、草酸镍、草酸镱、香叶酯、赤松素、硫化钇、硫酸锂、锡酸钠、氯苯基、甲硫基、硫化黑、精氨酸、cnidimola、甘氨酰、平平加、地衣酸、松脂素、锑酸钠、氟苯肼、硼酸盐、氯吡唑、硼酸锌
- 主营：前胡醇、阻燃剂、酸性橙、075-68-6)、硫酸锰、甲醇钙、脱乙基、肌氨酸、双黄酮、敌螨普、肉桂醇、甲基亚、肉桂醛、磷酸铜、磷酸铝、异丁酯、特戊醛、多菌灵、乙烯醇、乙氧基、对氨基、氟苯基、酸性红、羟乙基、白碳黑