Overview
4-Hydroxy-3-nitrobenzaldehyde is an organic compound with both hydroxyl and nitro functional groups attached to a benzaldehyde structure. It is primarily used as an intermediate in pharmaceutical and chemical synthesis. Due to its reactive nature, it serves as a precursor for more complex molecules, including dyes and active pharmaceutical ingredients (APIs). Its yellow crystalline form makes it easily identifiable in laboratory settings.
Physical and Chemical Properties
The compound appears as a yellow crystalline powder with a melting point around 126-128°C. It is soluble in common organic solvents such as ethanol and DMSO but has limited solubility in water. Its molecular structure includes an aldehyde group, a hydroxyl group, and a nitro group, which contribute to its reactivity. These functional groups make it a versatile building block in synthetic chemistry.
Main Applications
4-Hydroxy-3-nitrobenzaldehyde is widely used in the pharmaceutical industry for synthesizing intermediates in drug development. It is also employed in the production of dyes and pigments. In research laboratories, it serves as a reagent for studying organic reactions, particularly those involving nitro and aldehyde groups. Its applications extend to agrochemicals and specialty chemicals.
Safety and Storage
The compound is classified as an irritant and should be handled with care. Proper personal protective equipment (PPE), such as gloves and goggles, is recommended. Storage should be in a cool, dry place, away from direct sunlight and moisture. Containers should be tightly sealed to prevent degradation and contamination.
B2B Procurement Guide
When procuring 4-Hydroxy-3-nitrobenzaldehyde, verify the purity level (typically ≥98%) and request a Material Safety Data Sheet (MSDS) from the supplier. Compare prices from multiple vendors, as costs can vary based on quantity and purity. Bulk purchases may offer cost advantages, but ensure proper storage conditions are maintained. Reliable suppliers often provide certificates of analysis (CoA) for quality assurance.
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