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4-Hydroxy-3

Updated: 2026-07-29

Overview

4-Hydroxy-3-methylbenzoic acid is an organic compound that belongs to the class of hydroxybenzoic acids. It is commonly used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. The compound is known for its weakly acidic properties and stability under normal conditions. Its molecular structure includes a hydroxyl group and a methyl group attached to a benzene ring, which makes it a versatile building block in chemical synthesis. The compound is typically available as a white to off-white crystalline powder.

Physical and Chemical Properties

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The compound has a molecular weight of 152.15 g/mol and a melting point of approximately 180-185°C. It is soluble in water and polar solvents such as ethanol. The density and boiling point are not commonly reported, but the compound is known to be stable under standard storage conditions. The weakly acidic nature of 4-hydroxy-3-methylbenzoic acid makes it suitable for various chemical reactions, particularly those involving esterification and other organic transformations. Its solubility profile allows for easy handling in laboratory and industrial settings.

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Main Applications

4-Hydroxy-3-methylbenzoic acid is primarily used as an intermediate in the pharmaceutical industry. It serves as a key building block in the synthesis of drugs and other bioactive compounds. The compound is also employed in organic chemistry research and industrial chemical synthesis. Additionally, it finds applications in the production of dyes, fragrances, and other specialty chemicals. Its versatility and relatively mild properties make it a preferred choice for various chemical processes.

Safety and Storage

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When handling 4-hydroxy-3-methylbenzoic acid, it is important to use appropriate personal protective equipment, including gloves and safety goggles. The compound should be stored in a cool, dry place away from direct sunlight to maintain its stability. In case of accidental exposure, rinse the affected area with plenty of water and seek medical attention if necessary. The compound is generally considered to have low toxicity, but proper handling procedures should always be followed to minimize risks.

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B2B Procurement Guide

When procuring 4-hydroxy-3-methylbenzoic acid, buyers should verify the purity and quality of the product. It is advisable to request safety data sheets (SDS) and certificates of analysis (CoA) from suppliers to ensure compliance with industry standards. Prices can vary depending on the supplier and quantity purchased. Bulk orders may offer cost advantages, but buyers should also consider factors such as shipping, storage, and handling requirements when making procurement decisions.

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