4-Formyl-4'-biphenyl

Updated: 2026-07-15

Overview

4-Formyl-4'-biphenyl is an organic compound widely used in pharmaceutical and materials science industries. It serves as a key intermediate in the synthesis of various bioactive molecules and liquid crystal displays (LCDs). The compound's structure features a biphenyl core with a formyl functional group, making it versatile for further chemical modifications. Its applications extend to advanced materials, particularly in the production of liquid crystals, where its molecular properties contribute to the desired optical characteristics. The compound is typically synthesized through controlled oxidation or formylation reactions of biphenyl derivatives.

Physical and Chemical Properties

4-Formyl-4'-biphenyl appears as a white to off-white crystalline powder with a melting point of approximately 110-112°C. It is soluble in common organic solvents like ethanol, acetone, and dimethyl sulfoxide (DMSO), but exhibits negligible solubility in water. This solubility profile makes it suitable for organic synthesis processes. The compound's stability under normal storage conditions ensures its longevity, though exposure to strong oxidizing agents should be avoided. Its molecular weight of 182.22 g/mol and precise structural configuration contribute to its reactivity in targeted chemical reactions.

Main Applications

In the pharmaceutical industry, 4-Formyl-4'-biphenyl is a critical intermediate for synthesizing drugs targeting various therapeutic areas. Its role in constructing complex molecular architectures is invaluable for medicinal chemists. The compound also finds significant use in the production of liquid crystal materials, where it contributes to the alignment and switching properties essential for LCD technology. Additionally, it serves as a building block in organic electronic materials, enhancing the performance of devices like OLEDs and sensors.

Safety and Storage

Handling 4-Formyl-4'-biphenyl requires adherence to standard laboratory safety protocols. Personal protective equipment (PPE), including gloves and safety goggles, should be worn to prevent skin and eye contact. Adequate ventilation is recommended to avoid inhalation of dust or vapors. Storage should be in a cool, dry environment, away from incompatible substances such as strong oxidizers. The compound should be kept in tightly sealed containers to prevent moisture absorption and degradation. Proper labeling and hazard communication are essential for safe usage.

B2B Procurement Guide

When procuring 4-Formyl-4'-biphenyl, prioritize suppliers with verified quality control measures and certifications. Request certificates of analysis (CoA) to confirm purity and identity. Bulk purchases often yield cost savings, but ensure the supplier can meet your volume and delivery requirements. Consider logistical factors such as shipping conditions and lead times, especially for international transactions. Establish clear communication channels with suppliers to address any technical or regulatory concerns. Long-term partnerships with reputable manufacturers can ensure consistent quality and reliable supply.