4-Fluorothiobenzamide
Overview
4-Fluorothiobenzamide is a specialized organic compound primarily used as an intermediate in pharmaceutical synthesis. Its molecular structure includes a fluorine atom and a thiobenzamide group, making it valuable for constructing complex molecules. The compound is typically available as a white to off-white crystalline powder and is utilized in research and industrial applications. Due to its reactive functional groups, 4-Fluorothiobenzamide is often employed in medicinal chemistry for developing new drug candidates. Its role in organic synthesis is significant, particularly in reactions requiring fluorinated building blocks.
Physical and Chemical Properties
4-Fluorothiobenzamide is characterized by its molecular formula C7H6FNS and a molecular weight of 155.19 g/mol. It appears as a white to off-white crystalline powder and is soluble in common organic solvents like ethanol and DMSO, though it has limited solubility in water. The compound's stability under standard storage conditions makes it suitable for long-term use in laboratory settings. However, exposure to extreme temperatures or incompatible substances may lead to decomposition. Proper handling and storage are essential to maintain its integrity.
Main Applications
4-Fluorothiobenzamide is predominantly used as a building block in pharmaceutical synthesis. Its fluorinated and thiobenzamide components are valuable for creating bioactive molecules, particularly in drug discovery and development. Additionally, this compound finds applications in academic and industrial research, where it serves as a reagent for studying fluorinated organic compounds. Its versatility makes it a useful tool for chemists exploring new synthetic pathways.
Safety and Storage
When handling 4-Fluorothiobenzamide, it is crucial to follow safety protocols to minimize risks. The compound should be stored in a cool, dry place, away from light and moisture, to prevent degradation. Use appropriate PPE, including gloves and goggles, to avoid direct contact. In case of exposure, rinse affected areas with water and seek medical attention if necessary. Always refer to the material safety data sheet (MSDS) for detailed safety information and emergency procedures.
B2B Procurement Guide
Procuring 4-Fluorothiobenzamide requires careful consideration of purity, supplier reliability, and pricing. Buyers should request a Certificate of Analysis (COA) to verify the compound's quality and specifications. Prices typically range from $50 to $200 per gram, depending on purity and supplier. Establish long-term relationships with reputable suppliers to ensure consistent quality and availability. Bulk purchases may offer cost advantages for large-scale applications.
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