Overview
4-Fluorobenzophenone is an organic compound widely used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. It is characterized by its white to off-white crystalline appearance and moderate solubility in organic solvents. The compound is valued for its stability and reactivity, making it a versatile building block in organic synthesis. Chemically, 4-Fluorobenzophenone belongs to the class of aromatic ketones, featuring a fluorine atom substituted at the para position of one of the phenyl rings. This structural feature enhances its utility in various chemical reactions, particularly in the development of fluorinated compounds, which are increasingly important in modern chemistry.
Physical and Chemical Properties
4-Fluorobenzophenone exhibits a melting point range of 58-62°C, making it a solid at room temperature. It is soluble in common organic solvents such as ethanol, acetone, and dichloromethane but has limited solubility in water. The compound's molecular weight is 200.21 g/mol, and it is stable under standard storage conditions. Key chemical properties include its reactivity as a ketone, allowing it to participate in nucleophilic addition reactions, reductions, and other transformations. The presence of the fluorine atom introduces electronic effects that can influence the compound's reactivity and interaction with other molecules, making it a valuable intermediate in synthetic chemistry.
Main Applications
The primary use of 4-Fluorobenzophenone is as an intermediate in the pharmaceutical industry, where it serves as a precursor for the synthesis of active pharmaceutical ingredients (APIs) and other fluorinated compounds. Its applications extend to agrochemicals, where it is used to develop herbicides, insecticides, and fungicides with enhanced efficacy. In addition, 4-Fluorobenzophenone finds use in the production of specialty chemicals, including dyes, pigments, and liquid crystals. Its role in these industries underscores its importance as a versatile chemical building block, contributing to advancements in materials science and chemical manufacturing.
Safety and Storage
Handling 4-Fluorobenzophenone requires adherence to standard safety protocols to minimize exposure risks. The compound should be stored in a cool, dry place, protected from light and moisture to maintain its stability. Proper ventilation is recommended when working with the substance to avoid inhalation of dust or vapors. Personal protective equipment (PPE), such as gloves, goggles, and lab coats, should be worn to prevent skin and eye contact. In case of accidental exposure, rinse affected areas with plenty of water and seek medical attention if necessary. Safety data sheets (SDS) provided by suppliers should always be consulted for detailed handling and emergency measures.
B2B Procurement Guide
When procuring 4-Fluorobenzophenone, it is essential to evaluate suppliers based on their certifications, product purity, and consistency. Reputable suppliers should provide certificates of analysis (CoA) to verify the compound's quality and compliance with industry standards. Buyers should also consider factors such as packaging, lead times, and minimum order quantities to ensure a smooth supply chain. Establishing long-term relationships with reliable suppliers can help secure favorable pricing and ensure a steady supply of high-quality material. Additionally, staying informed about market trends and regulatory changes can aid in making informed procurement decisions.
Related Manufacturers
- 主营：聚乙烯亚胺、三甘醇二异辛酸酯3G8、TS-1钛硅分子筛、三硫代碳酸钠40%、六氯环三磷腈、5-甲基靛红、烷基苯磺酸酯、苯基次磷酸钠、甲巯咪唑、吡啶硫酮锌、焦磷酸哌嗪、热敏材料、油酸甲酯、曲酸
- 主营：甲基丙烯酸十二酯、甲基丙烯酸十六酯、甲基丙烯酸十八酯、二氟二苯甲酮、丙烯酸十二酯、丙烯酸十六酯、丙烯酸十八酯、V50引发剂、偶氮二异丁咪唑啉盐酸盐、N-乙酰己内酰胺、硅烷偶联剂、双马来酰亚胺、马来酸酯、缩水甘油酯、缩水甘油醚、甲基咪唑、N-异丙基丙烯酰胺、金属萃取剂
- 主营：离子液体、5-二甲基吡唑、咪唑、催化剂、阻燃剂、正丁醇锆、四氟硼酸锂、香兰基丁醚、氟化物、全氟辛基三甲氧基硅烷、丙酮肟、双酚E型氰酸酯、叔丁基乙烯基醚、钯碳催化剂、钛硅分子筛、硫酸烟酰苯胺、丙酮缩氨基硫脲
- 主营：化学试剂、氯金酸、卡尔费休、345、乙醇、异丙醇、药用辅料、依地酸钙钠、碳酸钠、盐酸氨丁三醇、龙胆酸、枸橼酸钠、甲醇、氢氧化钠、钴锰催化剂、硫酸锰、乙腈、色谱试剂、助剂、指示剂、醋酸锰、醋酸钴、氨丁三醇、尿素、硼酸
- 主营：氟二苯甲酮原料、麦芽糖酸、苯氧基环磷腈、甲巯基四氮唑
- 主营：有机原料、中间体、香精香料、催化剂、有机硅、表面活性剂
- 主营：化学品、香精香料、试剂、氟二苯甲酮、中间体、有机硅、橡胶树脂、催化剂、纳米材料
- 主营：聚苯胺、脯氨酸甲酯盐酸盐、苄基三甲基氯化铵
- 主营：杜仲素、对位酯、丙烯酸酯、44二氟苯甲酮、二氧化硫脲、乙基麦芽酚、饲料添加剂、油酸基硬脂酸、二苯基硅二醇
- 主营：架桥剂、YW100 锂萃取剂、端羧基液体丁腈橡胶、氟二苯甲酮、10-羟基癸酸、苯乙烯磷酸、肉豆蔻酸镁、硬脂酸钴、全氟三丁胺、乙烯基磷酸二乙酯、磷酸锰铁锂、β-磷酸三钙、十一烯酸、钨酸铝、1-乙炔基环已醇、间二异丙苯、锂硅合金、溴甲酚绿、生物活性玻璃、溴代海因树脂颗粒、红铝、龙涎酮、原丁酸三甲酯
- 主营：异辛醇、乳化剂、乙烯醚、345、醚羧酸、脂肪醇、分散剂、染色助剂、聚乙二醇、异构醇醚、泊洛沙姆、椰油酰胺、基羟乙基、烷基糖苷、特辛基酚、聚氧乙烯、嵌段聚醚、单油酸酯、异构十三醇、丙烯磺酸钠、氢化蓖麻油、丙烯酰胺基、醇醚葡糖苷、低泡渗透剂、甲酯乙氧基、癸基葡糖苷
- 主营：催化剂、胆酸、氧化剂、酶类、光引发剂、生物缓冲剂、交联剂、光敏剂、樟脑醌、十二氢十二硼双钠盐、磷钼酸、钼酸钾、6-二羟基吲哚、6-羟基吲哚、荧光增白剂、葡甲胺、N-乙基哌嗪、L-脯氨酸、鹅去氧胆酸、石胆酸
- 主营：异丙醇、二甲胺、二甲苯、84消毒液、苯基氯、二甘醇、石炭酸、乙二醇、丙烯酸、仲丁醇、水溶液、羟基苯、红铅丹、氨基苯、安息油、环己醇、正丁醇、单乙醇胺、医用酒精、液状石蜡、邻甲苯胺、杀菌消毒、乙基三胺、出口酒精、乙烯基苯
- 主营：氟二苯甲酮生产企业、阿昔洛韦侧链、化工原料
- 主营：二甲基亚砜、乙二醇、丙二醇、氟二苯甲酮、DMAC