4-Ethoxybenzoic Acid

Updated: 2026-07-25

Overview

p-Ethoxybenzoic Acid, also known as 4-Ethoxybenzoic Acid, is an organic compound belonging to the class of aromatic carboxylic acids. It features an ethoxy group (-OCH2CH3) attached to the para position of a benzoic acid ring. This compound is primarily used as an intermediate in pharmaceutical synthesis and fragrance production. Its chemical structure makes it valuable for introducing the ethoxybenzoate moiety into more complex molecules. The compound is typically supplied as a white crystalline powder and is stable under recommended storage conditions.

Physical and Chemical Properties

p-Ethoxybenzoic Acid has a molecular weight of 166.17 g/mol and appears as a white crystalline solid. It melts at 114-116°C and shows good solubility in organic solvents like ethanol and ether, while being only slightly soluble in water. The presence of both the carboxylic acid and ether functional groups gives this compound interesting chemical properties. The acid group allows for typical carboxylic acid reactions, while the ethoxy group provides some electron-donating character to the aromatic ring. These properties make it useful for various organic synthesis applications.

Main Applications

In the pharmaceutical industry, p-Ethoxybenzoic Acid serves as a building block for drug synthesis, particularly in the production of certain analgesics and anti-inflammatory agents. Its ethoxybenzoate derivatives are valuable in medicinal chemistry. The fragrance industry utilizes this compound in the synthesis of certain aromatic esters used in perfumery. Additionally, it finds use in organic synthesis as a starting material for more complex molecules, where the ethoxybenzoate group is desired.

Safety and Storage

While not extremely hazardous, p-Ethoxybenzoic Acid should be handled with standard chemical precautions. Avoid inhalation of dust and prevent skin or eye contact. Use appropriate personal protective equipment including gloves and safety glasses. For storage, keep the material in a tightly sealed container in a cool, dry place away from direct sunlight and moisture. Under these conditions, the compound remains stable for extended periods. In case of accidental exposure, wash affected areas with plenty of water and seek medical advice if irritation persists.

B2B Procurement Guide

When procuring p-Ethoxybenzoic Acid commercially, verify the CAS number (619-86-3) to ensure you're getting the correct compound. Check purity specifications which typically range from 97% to 99% for different applications. Consider ordering from suppliers who provide detailed analytical reports (COA) with each batch. Price varies based on quantity and purity, with bulk purchases generally offering better value. Lead times may vary depending on supplier stock levels, so plan procurement accordingly for production schedules.