Overview
4-Chloropropiophenone is an organic compound belonging to the class of aromatic ketones. It is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and fragrances. The compound is characterized by its white to off-white crystalline appearance and distinct chemical properties. Due to its role as a versatile intermediate, 4-Chloropropiophenone is in demand across various industries. Its synthesis involves chlorination and ketone formation processes, making it a valuable building block in organic chemistry.
Physical and Chemical Properties
4-Chloropropiophenone exhibits a melting point of approximately 35-38°C and a boiling point around 250-252°C. It is soluble in organic solvents such as ethanol and ether but has limited solubility in water. The compound's molecular weight is 168.62 g/mol, and it typically appears as a white to off-white crystalline powder. Key chemical properties include its reactivity as an aromatic ketone, making it suitable for further chemical transformations. Its stability under normal storage conditions ensures it can be handled safely in industrial settings.
Main Applications
The primary use of 4-Chloropropiophenone is as an intermediate in the pharmaceutical industry, where it serves as a precursor for various active pharmaceutical ingredients (APIs). It is also employed in the synthesis of agrochemicals, contributing to the production of pesticides and herbicides. Additionally, the compound finds applications in the fragrance industry, where it is used to create specific aromatic compounds. Its versatility and reactivity make it a valuable component in organic synthesis.
Safety and Storage
4-Chloropropiophenone should be handled with care, using appropriate personal protective equipment (PPE) such as gloves and goggles. Avoid inhalation and direct skin contact, as it may cause irritation. Proper ventilation is recommended when working with this compound. Storage conditions should include a cool, dry place away from direct sunlight and moisture. Containers must be tightly sealed to prevent contamination and degradation. Compliance with local safety regulations is essential for safe handling and disposal.
B2B Procurement Guide
When procuring 4-Chloropropiophenone, buyers should prioritize suppliers with verified certifications and a track record of consistent quality. Key factors to consider include purity levels (typically 98% or higher), batch consistency, and packaging standards. Price ranges vary depending on quantity and purity, with approximate costs between $50 and $100 per kg. Bulk purchases may offer cost advantages. Always request material safety data sheets (MSDS) and certificates of analysis (CoA) to ensure compliance with industry standards.
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