Overview
4-Chlorobenzophenone is an organic compound belonging to the benzophenone family. It is widely used as an intermediate in pharmaceuticals and agrochemicals due to its stable aromatic structure and reactivity. This compound is synthesized through Friedel-Crafts acylation of chlorobenzene with benzoyl chloride. Its versatility makes it valuable in various industrial applications, including UV stabilizers and photoinitiators.
Physical and Chemical Properties
4-Chlorobenzophenone appears as a white to light yellow crystalline powder with a characteristic mild odor. It has a melting point of 75-78°C and a boiling point of 332°C. The compound is soluble in common organic solvents like ethanol, acetone, and chloroform but exhibits limited solubility in water. Its stability under normal conditions makes it suitable for long-term storage when handled properly.
Main Applications
In the pharmaceutical industry, 4-Chlorobenzophenone serves as a key intermediate for synthesizing antihistamines, antipsychotics, and other active pharmaceutical ingredients (APIs). It is also used in agrochemicals for producing pesticides and herbicides. Additionally, its UV-absorbing properties make it useful in coatings and plastics to prevent photodegradation.
Safety and Storage
4-Chlorobenzophenone should be handled with care to avoid inhalation, ingestion, or skin contact. Proper personal protective equipment (PPE) such as gloves and goggles is recommended. Storage conditions should include a cool, dry environment away from direct sunlight and moisture. The compound is stable under normal conditions but may degrade when exposed to strong acids or bases.
B2B Procurement Guide
When procuring 4-Chlorobenzophenone, buyers should prioritize suppliers with certifications like ISO or GMP to ensure quality and consistency. Key factors to consider include purity levels (typically 98-99%), batch-to-batch consistency, and packaging options. Prices vary based on quantity and supplier, with bulk purchases often offering cost advantages.