Overview
4'-Bromovalerophenone is a brominated aromatic ketone primarily used as an intermediate in pharmaceutical synthesis. Its molecular structure includes a bromine atom attached to a phenyl ring, making it a versatile building block in organic chemistry. The compound is typically synthesized through bromination reactions and is known for its role in producing more complex molecules. In industrial settings, 4'-Bromovalerophenone is valued for its reactivity and ability to participate in various chemical transformations. It is commonly employed in the synthesis of active pharmaceutical ingredients (APIs) and other specialized chemicals. Due to its specific properties, it is often sourced by pharmaceutical and chemical manufacturers.
Physical and Chemical Properties
4'-Bromovalerophenone appears as a white to off-white crystalline powder with a melting point ranging between 45-50°C. It is soluble in common organic solvents such as ethanol, acetone, and dichloromethane but exhibits low solubility in water. The compound's bromine substituent enhances its reactivity, particularly in nucleophilic substitution reactions. The molecular weight of 4'-Bromovalerophenone is 241.12 g/mol, and its structure features a ketone functional group adjacent to a brominated phenyl ring. These characteristics make it a useful precursor in synthetic chemistry. Stability under normal conditions is good, but it should be protected from prolonged exposure to light and moisture to prevent degradation.
Main Applications
The primary application of 4'-Bromovalerophenone is in the pharmaceutical industry, where it serves as a key intermediate in the synthesis of various drugs. Its reactivity allows for the introduction of additional functional groups, making it valuable in multi-step synthetic routes. It is often used to produce compounds with therapeutic effects, such as analgesics or anti-inflammatory agents. Beyond pharmaceuticals, 4'-Bromovalerophenone finds use in academic and industrial research labs for developing novel organic compounds. Its role as a building block in organic synthesis underscores its importance in chemical manufacturing. The compound's versatility also extends to agrochemicals and specialty chemicals, though these applications are less common.
Safety and Storage
4'-Bromovalerophenone requires careful handling due to its potential health hazards. Direct contact with skin or eyes can cause irritation, and inhalation of dust or vapors should be avoided. Personal protective equipment (PPE), including gloves, goggles, and lab coats, is recommended when working with this chemical. Storage conditions are critical to maintaining the compound's stability. It should be kept in a tightly sealed container in a cool, dry place, away from direct sunlight and moisture. Incompatible materials include strong oxidizing agents, which may react violently. Proper labeling and segregation from incompatible substances are essential for safe storage in industrial or laboratory settings.
B2B Procurement Guide
When procuring 4'-Bromovalerophenone, B2B buyers should prioritize suppliers with verified credentials and a track record of delivering high-purity chemicals. Key considerations include CAS number verification (20320-89-8), purity specifications (typically ≥98%), and packaging options (e.g., sealed bottles or bulk containers). Price negotiations often depend on order volume, with larger quantities typically offering cost advantages. Buyers should also inquire about lead times, shipping conditions, and compliance with international safety regulations. Requesting certificates of analysis (CoA) and material safety data sheets (MSDS) is advisable to ensure product quality and regulatory compliance. Establishing long-term supplier relationships can enhance reliability and supply chain efficiency.
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