4-Aminobenzophenone

Updated: 2026-07-15

Overview

4-Aminobenzophenone (4-ABP) is an organic compound widely used as an intermediate in the synthesis of pharmaceuticals, dyes, and fine chemicals. Its molecular structure includes an amino group attached to a benzophenone core, which contributes to its reactivity and utility in various chemical processes. The compound is typically supplied as a yellow to light brown powder and requires careful handling due to its sensitivity to environmental factors. In industrial settings, 4-ABP is valued for its role in producing more complex molecules. Its applications span multiple sectors, including pharmaceuticals, where it serves as a building block for active pharmaceutical ingredients (APIs). The compound's stability under controlled conditions makes it a reliable choice for chemical synthesis.

Physical and Chemical Properties

4-Aminobenzophenone exhibits distinct physical and chemical properties that define its utility. It has a molecular weight of 197.23 g/mol and a melting point range of 125-128°C. The compound is soluble in common organic solvents such as ethanol and acetone but has limited solubility in water. Its light-sensitive nature necessitates storage in opaque containers to prevent degradation. The amino group in 4-ABP enhances its reactivity, making it a versatile intermediate in nucleophilic substitution and condensation reactions. Its benzophenone moiety contributes to its stability under normal conditions, though prolonged exposure to light or moisture should be avoided to maintain its integrity.

Main Applications

The primary use of 4-Aminobenzophenone lies in its role as an intermediate in pharmaceutical and dye manufacturing. In the pharmaceutical industry, it is employed in the synthesis of APIs, particularly those requiring benzophenone derivatives. Its reactivity allows for the introduction of additional functional groups, enabling the production of diverse therapeutic agents. In the dye industry, 4-ABP serves as a precursor for azo dyes and other colorants. Its ability to form stable, colored compounds makes it valuable for creating vibrant and durable dyes. Additionally, the compound finds use in fine chemical synthesis, where it contributes to the production of specialized chemicals for research and industrial applications.

Safety and Storage

Handling 4-Aminobenzophenone requires adherence to safety protocols to minimize risks. The compound should be stored in a cool, dry place, protected from light and moisture. Containers must be tightly sealed to prevent contamination and degradation. Personal protective equipment (PPE), including gloves and goggles, is recommended when handling the powder to avoid skin contact or inhalation. In case of exposure, immediate measures such as rinsing with water (for skin contact) or seeking fresh air (for inhalation) should be taken. Proper disposal methods must be followed to prevent environmental contamination. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency instructions.

B2B Procurement Guide

When procuring 4-Aminobenzophenone, B2B buyers should prioritize supplier reliability and product purity. Request certificates of analysis (CoA) to verify the compound's purity and ensure it meets the required specifications. Reputable suppliers often provide technical support and SDS, which are critical for safe handling and compliance. Price ranges vary depending on purity levels and order quantities. Bulk purchases may offer cost advantages, but buyers should balance cost with quality considerations. Establishing long-term relationships with trusted suppliers can ensure consistent quality and timely delivery. Additionally, consider logistics and storage requirements to maintain the compound's stability during transportation and storage.