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4-alkyne

Updated: 2026-07-20

Overview

4-Alkyne, also known as 1-Butyne, is an organic compound with a triple bond between the first and second carbon atoms in a four-carbon chain. It is a key building block in organic chemistry, particularly in the synthesis of more complex molecules. The compound is highly reactive due to the presence of the alkyne functional group, making it valuable in various chemical reactions. Its applications span across pharmaceuticals, agrochemicals, and materials science, where it serves as an intermediate in the production of specialty chemicals.

Physical and Chemical Properties

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4-Alkyne is a colorless gas or liquid under standard conditions, with a characteristic odor. It has a low boiling point of 8.1°C and a melting point of -125.7°C, indicating its volatility. The compound is slightly soluble in water but dissolves readily in common organic solvents like ethanol and ether. The triple bond in 4-Alkyne is highly reactive, making it prone to addition reactions such as hydrogenation, halogenation, and hydration. This reactivity is leveraged in synthetic chemistry to create more complex structures. Its flammability requires careful handling and storage to prevent accidents.

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Main Applications

4-Alkyne is primarily used as an intermediate in organic synthesis. It plays a crucial role in the production of pharmaceuticals, where it serves as a precursor for active pharmaceutical ingredients (APIs). Its reactivity allows for the creation of diverse molecular frameworks. In addition to pharmaceuticals, 4-Alkyne is used in the synthesis of agrochemicals, dyes, and polymers. Its ability to form carbon-carbon bonds efficiently makes it a valuable tool in materials science, enabling the development of advanced materials with tailored properties.

Safety and Storage

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Due to its high flammability, 4-Alkyne must be stored in a cool, dry place away from heat sources and open flames. Proper ventilation is essential to prevent the accumulation of flammable vapors. Containers should be tightly sealed and labeled with appropriate hazard warnings. Personal protective equipment (PPE), including gloves and safety goggles, should be worn when handling 4-Alkyne. In case of a spill, immediate action is required to eliminate ignition sources and ventilate the area. Emergency procedures should be in place to handle fires or exposures.

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B2B Procurement Guide

When procuring 4-Alkyne, it is essential to verify the supplier's credentials and ensure they provide comprehensive safety data sheets (SDS) and certificates of analysis (CoA). These documents confirm the product's purity and safety specifications. Buyers should also consider the intended application and required purity levels, as these factors influence the choice of supplier and pricing. Bulk purchases may offer cost advantages, but storage and handling capabilities must be assessed to ensure compliance with safety regulations. Reliable suppliers with a track record in chemical distribution are preferred.

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