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4-Acetoxybenzoic Acid

Updated: 2026-07-15

Overview

4-Acetoxybenzoic Acid (CAS 2345-34-8) is an organic compound belonging to the class of benzoic acid derivatives. It is widely used as an intermediate in pharmaceutical synthesis and organic chemistry. The compound is characterized by its white to off-white crystalline appearance and stability under normal conditions. Its molecular formula is C9H8O4, and it has a molecular weight of 180.16 g/mol. The presence of both acetoxy and carboxylic acid functional groups makes it a versatile building block for further chemical modifications. It is commonly sourced by B2B buyers in the chemical and pharmaceutical industries.

Physical and Chemical Properties

4-乙酰氧基苯甲酸 2345-34-8 白色晶体 药物中间体合成湖北兴恒业科技有限公司

4-Acetoxybenzoic Acid is a stable compound under standard conditions, with a melting point range of approximately 185-190°C. It is soluble in common organic solvents such as ethanol and acetone but exhibits limited solubility in water. The compound should be stored in a cool, dry environment to maintain its integrity. Key chemical properties include its reactivity with strong acids or bases, which may lead to decomposition. The acetoxy group can undergo hydrolysis under acidic or basic conditions, yielding acetic acid and 4-hydroxybenzoic acid. These properties are critical for its applications in synthetic chemistry.

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Main Applications

The primary use of 4-Acetoxybenzoic Acid is as an intermediate in pharmaceutical synthesis. It serves as a precursor for the production of various active pharmaceutical ingredients (APIs) and specialty chemicals. Its functional groups allow for further derivatization, making it valuable in organic synthesis. In addition to pharmaceuticals, it is occasionally used in research laboratories for the development of novel compounds. Its role as a building block in organic chemistry underscores its importance in industrial and academic settings. B2B buyers often procure it in bulk for large-scale manufacturing processes.

Safety and Storage

4-乙酰氧基苯甲酸 CAS号2345-34-8 含量98% 乙酰水杨酸杂质11 朗博万湖北朗博万生物医药有限公司

Handling 4-Acetoxybenzoic Acid requires adherence to safety protocols to prevent exposure. Personal protective equipment (PPE), including gloves and goggles, should be worn when working with the compound. Avoid inhalation, ingestion, or direct skin contact to minimize health risks. Storage conditions are critical to maintaining the compound's stability. It should be kept in a tightly sealed container, away from moisture and direct sunlight. In case of accidental exposure, rinse affected areas with water and seek medical attention if necessary. Proper disposal methods should follow local regulations for chemical waste.

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B2B Procurement Guide

When procuring 4-Acetoxybenzoic Acid, B2B buyers should prioritize suppliers with verified credentials and a track record of reliability. Key factors to consider include purity levels (typically 98% or higher), packaging options, and compliance with industry standards. The reference price range is approximately $50-$100 per kilogram, though prices may vary based on quantity and supplier. Buyers should request certificates of analysis (CoA) to confirm the compound's specifications. Bulk purchases may qualify for discounts, but ensure storage capacity aligns with delivery schedules to avoid degradation.

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