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4-Acetamidoacetophenone

Updated: 2026-07-24

Overview

4-Acetamidoacetophenone is an organic compound with the molecular formula C10H11NO2. It is commonly used as an intermediate in pharmaceutical synthesis and chemical research. The compound appears as a white to off-white crystalline powder and is known for its stability under normal storage conditions. Its primary role in industrial applications includes serving as a precursor in the synthesis of more complex molecules, particularly in the pharmaceutical industry. The compound's properties make it suitable for various organic reactions, including condensation and substitution processes.

Physical and Chemical Properties

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4-Acetamidoacetophenone has a molecular weight of 177.20 g/mol and a melting point range of approximately 148-152°C. It is soluble in common organic solvents such as ethanol and acetone but has limited solubility in water. The compound is stable under standard conditions but may degrade when exposed to strong oxidizing agents. The crystalline structure of 4-Acetamidoacetophenone contributes to its stability and ease of handling in laboratory and industrial settings. Its solubility profile makes it versatile for use in various chemical reactions and formulations.

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Main Applications

The primary application of 4-Acetamidoacetophenone is in the pharmaceutical industry, where it serves as an intermediate in the synthesis of active pharmaceutical ingredients (APIs). It is also used in organic chemistry research for developing new compounds and studying reaction mechanisms. In addition to pharmaceuticals, this compound finds use in specialty chemical manufacturing, where it acts as a building block for more complex molecules. Its role in these industries highlights its importance in advancing chemical and medical research.

Safety and Storage

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When handling 4-Acetamidoacetophenone, it is essential to follow standard safety protocols to avoid exposure. Personal protective equipment (PPE), such as gloves and goggles, should be worn to prevent skin and eye contact. The compound should be stored in a cool, dry place, away from direct sunlight and moisture to maintain its stability. In case of accidental exposure, rinse the affected area with plenty of water and seek medical attention if necessary. Proper storage and handling minimize risks and ensure the compound's longevity and effectiveness in applications.

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B2B Procurement Guide

When procuring 4-Acetamidoacetophenone, buyers should verify the CAS number (7463-31-2) and purity specifications to ensure they receive the correct product. It is advisable to source from reputable suppliers who provide batch-specific certificates of analysis (CoA). Price ranges can vary depending on the supplier and order quantity, so obtaining multiple quotes is recommended. Buyers should also consider logistics and storage requirements to maintain the compound's quality during transit and upon receipt.

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