Overview
3-Oxo-ursolic acid-28-methyl ester is a derivative of ursolic acid, a naturally occurring pentacyclic triterpenoid. This compound is synthesized for its enhanced stability and solubility compared to its parent molecule. It is primarily utilized in research settings, particularly in pharmaceutical and cosmetic industries, due to its potential biological activities. Ursolic acid derivatives, including this ester, are studied for their anti-inflammatory, anticancer, and antimicrobial properties. The modification at the 3-position (keto group) and 28-position (methyl ester) alters its pharmacokinetic profile, making it a valuable compound for drug development and formulation studies.
Physical and Chemical Properties
The compound appears as a white to off-white crystalline powder with a melting point around 220-230°C. It is soluble in common organic solvents such as dimethyl sulfoxide (DMSO) and ethanol but exhibits poor solubility in water. The molecular weight is 484.71 g/mol, and the molecular formula is C31H48O4. Stability is a key feature, with the compound remaining intact under recommended storage conditions. It is non-hygroscopic, which minimizes degradation due to moisture. These properties make it suitable for long-term storage and use in various experimental protocols.
Main Applications
3-Oxo-ursolic acid-28-methyl ester is widely used in pharmaceutical research, particularly in studies focusing on its anti-inflammatory and anticancer effects. Its modified structure enhances bioavailability, making it a candidate for drug delivery systems. In the cosmetic industry, this compound is explored for its potential skin-beneficial properties, including anti-aging and antioxidant effects. Additionally, it serves as a reference standard in analytical chemistry for quality control and method validation in laboratories.
Safety and Storage
Handling 3-Oxo-ursolic acid-28-methyl ester requires standard laboratory safety practices. Avoid inhalation, ingestion, and direct skin contact by using appropriate personal protective equipment (PPE) such as gloves and safety goggles. For storage, keep the compound in a cool, dry place, protected from light and moisture. Properly sealed containers are recommended to prevent contamination and degradation. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety and handling instructions.
B2B Procurement Guide
When procuring 3-Oxo-ursolic acid-28-methyl ester, it is essential to verify the supplier's credentials and the product's purity. Request a Certificate of Analysis (COA) to confirm the compound's specifications and ensure compliance with your research or production needs. Price varies based on purity and quantity, typically ranging from $50 to $200 per gram. Bulk purchases may offer cost savings. Consider lead times and shipping conditions, especially for international orders, to ensure the product arrives in optimal condition.
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