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3-Morpholinone

Updated: 2026-07-15

Overview

3-Morpholinone is a heterocyclic compound featuring a morpholine ring with a ketone functional group. It serves as a versatile intermediate in organic synthesis, particularly in the pharmaceutical and agrochemical industries. The compound's unique structure allows it to participate in various chemical reactions, making it valuable for producing active pharmaceutical ingredients (APIs) and specialty chemicals. Due to its stability and solubility, 3-morpholinone is favored in laboratory and industrial settings. It is typically synthesized through controlled oxidation or other specialized processes. B2B buyers should prioritize suppliers with strict quality control measures to ensure consistency in purity and performance.

Physical and Chemical Properties

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3-Morpholinone appears as a white to off-white crystalline powder with a molecular weight of 101.10 g/mol. It is soluble in water and common organic solvents, facilitating its use in diverse formulations. The compound has a melting point of approximately 90-95°C, though exact values may vary based on purity. Key chemical properties include its stability under normal conditions and hygroscopic nature, requiring proper storage to prevent moisture absorption. Its reactivity with strong oxidizing agents and acids should be considered during handling. Analytical techniques like HPLC and NMR are commonly used to verify its purity and structural integrity.

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Main Applications

3-Morpholinone is primarily used as an intermediate in pharmaceutical synthesis, contributing to the production of antibiotics, antivirals, and other APIs. Its role in agrochemicals includes the development of herbicides and fungicides, where it enhances efficacy and stability. In specialty chemistry, the compound is employed in polymer modification and corrosion inhibitors. Research applications also explore its potential in novel drug formulations. B2B buyers should align procurement with end-use requirements, ensuring the product meets regulatory standards for intended applications.

Safety and Storage

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Handle 3-morpholinone with appropriate personal protective equipment (PPE), including gloves and goggles, to avoid skin and eye contact. Inhalation of dust should be prevented by working in well-ventilated areas or using respiratory protection. Store the compound in a cool, dry place, preferably in airtight containers to minimize exposure to moisture. Incompatible materials include strong oxidizers and acids. Spills should be contained and cleaned promptly using inert absorbents. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal guidelines.

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B2B Procurement Guide

When sourcing 3-morpholinone, prioritize suppliers with certifications like ISO or GMP to ensure quality and compliance. Request certificates of analysis (CoA) to verify purity, typically ranging from 98% to 99.5% for industrial use. Bulk purchases may offer cost advantages, but confirm logistical capabilities for safe transportation. Evaluate supplier reliability through customer reviews and sample testing. For niche applications, custom synthesis options may be available. Price ranges vary; obtain quotes from multiple vendors for comparison.

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