Overview
3-Methylquinoline is an organic compound belonging to the quinoline family, characterized by a methyl group at the 3-position of the quinoline ring. It is a colorless to pale yellow liquid with a distinct aromatic odor. The compound is widely used in the synthesis of pharmaceuticals, dyes, and agrochemicals due to its versatile chemical properties. Quinoline derivatives, including 3-methylquinoline, are valued for their role as intermediates in organic synthesis. The compound's reactivity and stability make it a preferred choice for industrial applications, particularly in the production of antimalarial drugs and other therapeutic agents.
Physical and Chemical Properties
3-Methylquinoline has a molecular weight of 143.19 g/mol and a density of 1.06 g/cm³. It is a volatile liquid with a boiling point of 248-250°C and a melting point of -15°C. The compound is soluble in common organic solvents such as ethanol and ether but exhibits limited solubility in water. Key chemical properties include its aromatic nature and reactivity as a base, enabling it to participate in various chemical reactions. The presence of the methyl group enhances its stability and influences its reactivity in substitution and addition reactions, making it useful in synthetic chemistry.
Main Applications
3-Methylquinoline is primarily used in the pharmaceutical industry as an intermediate in the synthesis of antimalarial drugs and other therapeutic compounds. Its derivatives are also employed in the production of dyes and pigments, particularly for textiles and inks. In agrochemicals, 3-methylquinoline serves as a building block for pesticides and herbicides. Its chemical properties allow it to act as a precursor in the development of compounds that target specific pests or weeds, contributing to efficient crop protection strategies.
Safety and Storage
3-Methylquinoline is classified as harmful if swallowed or inhaled and can cause skin and eye irritation. Proper handling procedures, including the use of gloves, goggles, and respiratory protection, are essential when working with this compound. Storage should be in a cool, dry, well-ventilated area away from heat sources and open flames. Containers must be tightly sealed to prevent evaporation and contamination. In case of spills, absorb with inert material and dispose of according to local regulations.
B2B Procurement Guide
When procuring 3-methylquinoline, buyers should prioritize suppliers with verified credentials and a track record of delivering high-purity products. Key considerations include CAS number verification, batch testing reports, and compliance with regulatory standards. Bulk purchases may qualify for discounts, but buyers should assess storage capabilities to ensure safe handling. Logistics planning is crucial, especially for international shipments, to avoid delays and ensure product integrity upon arrival.
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