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3-Methoxybenzamide

Updated: 2026-07-15

Overview

3-Methoxybenzamide is an organic compound belonging to the benzamide class. It is widely used in the pharmaceutical industry as an intermediate for synthesizing various drugs. The compound is known for its stability and relatively simple synthesis process, making it a preferred choice in organic chemistry laboratories and industrial applications. Its molecular structure includes a methoxy group attached to the benzene ring, which influences its reactivity and solubility. This compound is typically available as a white to off-white crystalline powder, ensuring ease of handling and storage.

Physical and Chemical Properties

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3-Methoxybenzamide exhibits a melting point of approximately 120-122°C, indicating its stability at room temperature. It is soluble in common organic solvents such as ethanol and acetone but has limited solubility in water. This property makes it suitable for use in non-aqueous reaction environments. The compound's molecular weight is 151.16 g/mol, and it remains stable under normal storage conditions. However, exposure to extreme heat or strong oxidizing agents should be avoided to prevent decomposition. Its crystalline form ensures minimal degradation over time when stored properly.

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Main Applications

The primary use of 3-Methoxybenzamide is as a pharmaceutical intermediate. It serves as a building block in the synthesis of various active pharmaceutical ingredients (APIs). Its reactivity and stability make it valuable in producing compounds with potential therapeutic effects. Additionally, this compound is utilized in organic synthesis for creating more complex molecules. Researchers appreciate its predictable behavior in reactions, which aids in developing new chemical entities. Its applications extend to academic research, where it is often used to study reaction mechanisms and synthetic pathways.

Safety and Storage

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Handling 3-Methoxybenzamide requires standard laboratory safety precautions. Avoid direct contact with skin or eyes, and use protective gloves and goggles. Inhalation of dust should be prevented by working in a well-ventilated area or using a fume hood. Storage conditions should be cool, dry, and away from direct sunlight. The compound should be kept in a tightly sealed container to prevent moisture absorption. In case of accidental exposure, rinse affected areas with plenty of water and seek medical attention if necessary.

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B2B Procurement Guide

When procuring 3-Methoxybenzamide, prioritize suppliers with a proven track record of quality and reliability. Request certificates of analysis (CoA) to verify purity and composition. Bulk purchases may offer cost advantages, but ensure proper storage facilities are available. Consider the supplier's compliance with Good Manufacturing Practices (GMP) if the compound is intended for pharmaceutical use. Lead times and shipping conditions should also be evaluated to prevent delays or damage during transit. For reference, prices commonly range between $50 and $100 per kg, depending on quantity and purity.

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