3-Iodobenzyl bromide

Updated: 2026-08-25

Overview

3-Iodobenzyl bromide is a halogenated organic compound primarily used as an intermediate in pharmaceutical and chemical synthesis. It is characterized by its reactivity due to the presence of both bromine and iodine atoms, making it valuable for various organic transformations. This compound is typically supplied as a crystalline solid and is commonly utilized in research laboratories and industrial settings. Its applications span across the development of active pharmaceutical ingredients (APIs) and specialty chemicals.

Physical and Chemical Properties

3-Iodobenzyl bromide is a pale yellow to light brown crystalline solid with a molecular weight of 296.93 g/mol. It is soluble in common organic solvents such as dichloromethane, ethanol, and acetone, which facilitates its use in various synthetic processes. The compound's density is approximately 2.1 g/cm³, and it exhibits reactivity typical of halogenated benzyl compounds. Its stability under normal conditions makes it suitable for storage and handling in controlled environments, though precautions are necessary to avoid exposure to moisture and light.

Main Applications

The primary use of 3-iodobenzyl bromide is as an intermediate in the synthesis of pharmaceuticals and specialty chemicals. Its reactive halogen groups enable it to participate in cross-coupling reactions, substitutions, and other key transformations in organic chemistry. In the pharmaceutical industry, it is often employed in the development of APIs and other bioactive molecules. Additionally, it finds applications in materials science and agrochemical research, where halogenated intermediates are frequently required.

Safety and Storage

3-Iodobenzyl bromide is corrosive and can cause skin and eye irritation. Proper handling procedures, including the use of gloves, goggles, and protective clothing, are essential to minimize exposure risks. Storage should be in a cool, dry place, away from direct sunlight and moisture. Containers must be tightly sealed to prevent degradation and contamination. In case of spills, neutralization with appropriate agents and proper disposal methods should be followed to ensure environmental safety.

B2B Procurement Guide

When procuring 3-iodobenzyl bromide, B2B buyers should verify the supplier's credentials and ensure compliance with safety and purity standards. Key factors to consider include the compound's purity level, packaging, and handling instructions. Prices vary depending on quantity and supplier, so obtaining multiple quotes is advisable. Buyers should also confirm the availability of technical support and documentation, such as safety data sheets (SDS), to facilitate safe and efficient use in industrial or research settings.