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3-Hydroxytricin

Updated: 2026-08-05

Overview

3-Hydroxylupulone is a natural compound derived from hops (Humulus lupulus), a key ingredient in beer brewing. It belongs to the class of bitter acids, which contribute to the distinct flavor profile of beer. This compound is structurally related to lupulone and is known for its antimicrobial properties, making it valuable in both brewing and food preservation. Research indicates that 3-hydroxylupulone plays a role in enhancing beer stability by inhibiting microbial growth. Its applications extend beyond brewing, with potential uses in pharmaceutical and food industries due to its bioactive properties.

Physical and Chemical Properties

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3-Hydroxylupulone appears as a yellowish crystalline powder with a molecular weight of 414.58 g/mol. It is soluble in organic solvents like ethanol but has limited solubility in water. The compound exhibits stability under typical brewing conditions, retaining its properties during fermentation and storage. The melting point of 3-hydroxylupulone is approximately 120-125°C, though precise data on boiling point and density are not widely documented. Its bitter taste and antimicrobial efficacy are key characteristics that make it useful in industrial applications.

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Main Applications

The primary application of 3-hydroxylupulone is in the beer brewing industry, where it contributes to bitterness and acts as a natural preservative. Its antimicrobial properties help extend the shelf life of beer by inhibiting spoilage microorganisms. Beyond brewing, 3-hydroxylupulone is explored for potential uses in food preservation and pharmaceuticals. Some studies suggest it may have bioactive effects, though further research is needed to confirm its efficacy in these areas.

Safety and Storage

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3-Hydroxylupulone should be handled with care, using gloves and protective equipment to avoid skin contact or inhalation. While not highly toxic, prolonged exposure may cause irritation. Proper storage involves keeping the compound in a cool, dry place, protected from light and moisture to maintain stability. For industrial use, compliance with safety regulations is essential. Suppliers typically provide Material Safety Data Sheets (MSDS) detailing handling and storage guidelines.

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B2B Procurement Guide

When procuring 3-hydroxylupulone, B2B buyers should prioritize purity and supplier reliability. The compound is typically sold in bulk, with prices varying based on purity levels and market demand. Buyers should verify certificates of analysis (CoA) to ensure quality. It’s advisable to source from reputable suppliers specializing in hop derivatives. Consider testing small batches before large-scale purchases to confirm suitability for intended applications.

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