Overview
3-Hydroxyphloretin is a flavonoid compound derived from the hydrogenation of phloretin, a dihydrochalcone found in apples and other fruits. It is known for its antioxidant properties and potential health benefits, making it a subject of interest in both the food and pharmaceutical industries. This compound is often studied for its role in reducing oxidative stress and inflammation. Its natural occurrence in fruits like apples and pears has led to research into its potential as a functional food additive or nutraceutical ingredient.
Physical and Chemical Properties
3-Hydroxyphloretin typically appears as a pale yellow to white crystalline powder. It has a molecular weight of 274.27 g/mol and is soluble in organic solvents such as ethanol, methanol, and DMSO, but only slightly soluble in water. The compound exhibits strong antioxidant activity, which is attributed to its ability to scavenge free radicals. Its chemical structure includes hydroxyl groups that contribute to its solubility and reactivity, making it useful in various biochemical applications.
Main Applications
3-Hydroxyphloretin is primarily used in the food industry as a natural antioxidant to extend shelf life and enhance the nutritional profile of products. It is also explored in nutraceuticals for its potential health benefits, including anti-inflammatory and anticancer effects. In pharmaceutical research, this compound is studied for its role in modulating cellular pathways related to oxidative stress and inflammation. Its applications extend to cosmetic formulations, where it may help protect skin from environmental damage.
Safety and Storage
While 3-Hydroxyphloretin is generally considered safe, proper handling is essential to avoid potential health risks. It should be stored in a cool, dry place, protected from light and moisture to maintain stability. Safety data sheets (SDS) should be consulted before use, and personal protective equipment (PPE) such as gloves and goggles should be worn when handling the compound. In case of exposure, rinse thoroughly with water and seek medical advice if necessary.
B2B Procurement Guide
When procuring 3-Hydroxyphloretin, B2B buyers should prioritize suppliers who provide detailed documentation, including certificates of analysis (COA) and material safety data sheets (MSDS). These documents ensure the product meets quality and safety standards. Buyers should also consider the compound's purity, which can significantly impact its effectiveness in applications. Prices vary based on purity and supplier, so obtaining multiple quotes and verifying supplier credibility is advisable.
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