Overview
3-Bromofluorenone is a brominated derivative of fluorenone, a compound widely used in organic chemistry and pharmaceutical research. It serves as a key intermediate in the synthesis of various complex molecules. The compound is characterized by its pale yellow crystalline appearance and its solubility in organic solvents. Due to its reactivity and structural properties, 3-Bromofluorenone is particularly valuable in the development of pharmaceuticals and advanced materials. Its role in organic synthesis makes it a staple in research laboratories and industrial settings.
Physical and Chemical Properties
3-Bromofluorenone is a solid at room temperature, with a melting point ranging between 130-135°C. It is soluble in common organic solvents such as ethanol, acetone, and dichloromethane but is insoluble in water. The compound exhibits typical aromatic ketone properties, including reactivity towards nucleophiles and electrophiles. The presence of the bromine atom enhances its utility in cross-coupling reactions, making it a versatile building block in synthetic chemistry. Its molecular weight is 259.10 g/mol, and it is typically supplied as a fine crystalline powder.
Main Applications
3-Bromofluorenone is primarily used as an intermediate in the synthesis of pharmaceuticals and specialty chemicals. It is a key precursor in the production of fluorenone derivatives, which are employed in dyes, pigments, and optoelectronic materials. In pharmaceutical research, this compound is utilized to develop active pharmaceutical ingredients (APIs) and other biologically active molecules. Its role in organic synthesis extends to the creation of complex heterocyclic compounds, which are essential in medicinal chemistry.
Safety and Storage
Handling 3-Bromofluorenone requires caution due to its potential health hazards. It may cause irritation to the skin, eyes, and respiratory system. Proper personal protective equipment (PPE), including gloves and goggles, should be worn when working with this compound. Storage conditions should include a cool, dry environment, away from direct sunlight and moisture. Containers must be tightly sealed to prevent contamination and degradation. Safety data sheets (SDS) should always be consulted before use.
B2B Procurement Guide
When procuring 3-Bromofluorenone, buyers should prioritize suppliers who provide detailed product specifications, including purity levels and CAS number verification. It is advisable to request samples for quality testing before large-scale purchases. Price ranges vary depending on purity and supplier, with higher purity grades commanding premium prices. Bulk purchases may offer cost advantages, but storage and handling capabilities should be assessed to ensure compliance with safety standards.
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