Overview
3-Bromo-4'-chloro-1,1'-biphenyl is a halogenated biphenyl derivative widely used in specialized chemical synthesis. Its molecular structure combines bromine and chlorine substituents, enhancing reactivity for cross-coupling reactions and pharmaceutical intermediate production. This compound is favored in B2B markets for its stability and versatility in organic transformations. It is typically supplied as a crystalline solid, with purity levels critical for industrial applications.
Physical and Chemical Properties
The compound exhibits typical properties of halogenated aromatics, including low water solubility and high solubility in organic solvents like ethanol or acetone. Its molecular weight of 267.55 g/mol reflects the combined mass of bromine and chlorine atoms. Thermal properties such as melting and boiling points are manufacturer-dependent but generally align with similar biphenyl derivatives. The crystalline form ensures ease of handling in controlled environments.
Main Applications
3-Bromo-4'-chloro-1,1'-biphenyl serves as a key intermediate in pharmaceutical synthesis, particularly for active pharmaceutical ingredients (APIs) requiring biphenyl scaffolds. Its halogen atoms enable efficient Suzuki-Miyaura and other cross-coupling reactions. In agrochemical research, it contributes to the development of novel pesticides. The compound also finds niche use in material science for creating specialized polymers and liquid crystals.
Safety and Storage
As a halogenated compound, it requires careful handling with nitrile gloves and fume hoods to prevent exposure. Skin contact may cause irritation, and inhalation of dust should be avoided. Long-term storage recommendations include airtight containers under inert gas (e.g., nitrogen) to prevent degradation. Compatibility checks with storage materials are essential, as some plastics may react with halogenated compounds.
B2B Procurement Guide
Industrial buyers should prioritize suppliers with ISO certification and detailed COA (Certificate of Analysis). Purity levels of ≥98% are typical for research applications, while ≥95% may suffice for some bulk processes. Lead times vary; specialty chemicals like this often require 4-8 weeks for production. Consider requesting samples for HPLC/GC-MS validation before large purchases. MOQs (Minimum Order Quantities) commonly start at 100g for lab-scale suppliers.
Related Manufacturers
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