Overview
3-Acetylindole is an organic compound derived from indole, featuring an acetyl group at the 3-position. It is widely used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and fragrances. The compound's structure makes it a valuable building block for more complex molecules. Due to its reactivity, 3-acetylindole is commonly employed in heterocyclic chemistry and medicinal chemistry research. It is available as a pale yellow to brown crystalline powder and is typically sourced by B2B buyers in bulk quantities.
Physical and Chemical Properties
3-Acetylindole has a molecular weight of 159.18 g/mol and appears as a pale yellow to brown crystalline solid. It has a melting point of approximately 188-190°C, making it stable under standard conditions. The compound is soluble in common organic solvents like ethanol and acetone but has limited solubility in water. Its chemical structure includes an indole ring system with an acetyl substituent, which enhances its reactivity in various synthetic applications. The compound's stability and solubility profile make it suitable for use in laboratory and industrial settings.
Main Applications
3-Acetylindole is primarily used as an intermediate in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs). It is also employed in agrochemical production to create pesticides and herbicides with specific biological activities. Additionally, the compound finds use in the fragrance industry, where it contributes to the synthesis of aromatic compounds. Its versatility in organic synthesis makes it a valuable tool for researchers and manufacturers alike.
Safety and Storage
When handling 3-acetylindole, appropriate safety measures such as gloves, goggles, and lab coats should be worn to prevent skin and eye contact. The compound should be stored in a cool, dry place, away from direct sunlight and moisture to maintain its stability. In case of accidental exposure, rinse affected areas with plenty of water and seek medical attention if necessary. Proper ventilation is recommended when working with the compound to avoid inhalation of dust or vapors.
B2B Procurement Guide
B2B buyers should verify the purity and quality of 3-acetylindole by requesting a Certificate of Analysis (COA) from suppliers. It is advisable to source the compound from reputable manufacturers with a track record of reliable production. Purchasing in bulk may offer cost advantages, but buyers should also consider storage requirements and shelf life. Comparing prices from multiple suppliers can help secure competitive rates, though quality should not be compromised for cost savings.
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