Overview
2,6-Dihydroxybenzaldehyde (2,6-DHB) is an organic compound belonging to the class of phenolic aldehydes. It is characterized by the presence of two hydroxyl groups and an aldehyde group on a benzene ring, making it a versatile intermediate in chemical synthesis. The compound is commonly used in the pharmaceutical and dye industries due to its reactive functional groups. 2,6-DHB is synthesized through various chemical processes, including the formylation of resorcinol. Its white to light yellow crystalline form and moderate solubility in water and organic solvents make it suitable for diverse applications. The compound is also studied for its potential biological activities, including antioxidant properties.
Physical and Chemical Properties
2,6-Dihydroxybenzaldehyde is a solid at room temperature with a melting point ranging between 135-140°C. It is soluble in water, ethanol, and acetone, which facilitates its use in various chemical reactions. The compound's molecular weight is 138.12 g/mol, and its structure includes reactive hydroxyl and aldehyde groups. The presence of these functional groups allows 2,6-DHB to participate in reactions such as condensation, oxidation, and electrophilic substitution. Its solubility profile and stability under standard conditions make it a reliable reagent in laboratory and industrial settings. However, it should be protected from prolonged exposure to light and moisture to maintain its integrity.
Main Applications
2,6-Dihydroxybenzaldehyde is primarily used as an intermediate in the synthesis of pharmaceuticals, dyes, and other organic compounds. In the pharmaceutical industry, it serves as a building block for active pharmaceutical ingredients (APIs) and specialty chemicals. Its reactive aldehyde group is particularly valuable in forming Schiff bases and other derivatives. In the dye industry, 2,6-DHB is utilized to produce colorants and pigments. Its ability to form complexes with metals enhances its utility in creating vibrant and stable dyes. Additionally, the compound is explored in research for its potential antioxidant and antimicrobial properties, though these applications are still under investigation.
Safety and Storage
Handling 2,6-Dihydroxybenzaldehyde requires standard laboratory safety precautions. It is advisable to wear gloves, protective clothing, and eye protection to avoid skin and eye contact. Inhalation of dust or vapors should be prevented by working in a well-ventilated area or using a fume hood. Storage conditions include keeping the compound in a cool, dry place away from direct sunlight and moisture. It should be stored in a tightly sealed container to prevent degradation. In case of accidental exposure, rinse affected areas with plenty of water and seek medical attention if necessary. Proper disposal methods should be followed to minimize environmental impact.
B2B Procurement Guide
When procuring 2,6-Dihydroxybenzaldehyde, B2B buyers should prioritize suppliers with verified certifications and a track record of quality. Key factors to consider include purity levels (typically 98% or higher), CAS number verification, and packaging options that ensure product stability during transit. Price negotiations should account for bulk purchase discounts, with reference prices ranging approximately $50-$100 per kilogram. Buyers are advised to request samples for quality testing before large-scale orders. Additionally, inquire about lead times, shipping conditions, and compliance with regional chemical regulations to avoid logistical or legal issues.
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