Overview
25-Methoxyalisol is a triterpenoid compound isolated from the rhizomes of Alisma plantago-aquatica, a plant widely used in traditional Chinese medicine (TCM). It is structurally related to alisol derivatives, known for their diuretic and anti-inflammatory properties. The compound has garnered interest for its potential therapeutic applications, particularly in treating conditions like edema and kidney disorders. Research into 25-Methoxyalisol is still in early stages, but preliminary studies suggest it may modulate lipid metabolism and exhibit hepatoprotective effects. Its molecular structure includes a methoxy group at the 25th position, which may enhance its bioavailability compared to other alisol variants.
Physical and Chemical Properties
25-Methoxyalisol is a crystalline solid with a molecular weight of 516.76 g/mol. Its solubility profile favors organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO), while it remains largely insoluble in water. The compound is stable under standard conditions but may degrade upon prolonged exposure to light or humidity. The melting point ranges between 180–185°C, typical for triterpenoids. Spectroscopic methods (NMR, IR) are commonly used for identification and purity assessment. Its stability under varying pH conditions is still under investigation, though neutral to slightly acidic environments are recommended for storage.
Main Applications
In TCM, 25-Methoxyalisol is primarily utilized as a diuretic to address water retention and support kidney function. Modern research explores its potential in treating metabolic syndromes, including hyperlipidemia and non-alcoholic fatty liver disease (NAFLD), due to its purported lipid-regulating effects. Pharmaceutical studies focus on its anti-inflammatory and antioxidative properties, which may contribute to cardiovascular and hepatic protection. However, clinical applications remain experimental, requiring further validation. B2B buyers often procure this compound for academic research, drug development, or niche herbal formulations.
Safety and Storage
While 25-Methoxyalisol is not classified as highly toxic, standard laboratory precautions should be followed. Use personal protective equipment (PPE) such as gloves and goggles to prevent skin or eye contact. Inhalation of powder should be avoided; work in a fume hood if handling large quantities. Storage requires protection from moisture and light. Sealed containers with desiccants are recommended, ideally at temperatures below 25°C. Stability data for long-term storage is limited, so periodic purity checks via HPLC are advisable for critical applications.
B2B Procurement Guide
When sourcing 25-Methoxyalisol, prioritize suppliers with certified analytical reports (e.g., HPLC ≥98% purity). Reputable manufacturers often provide batch-specific COAs (Certificates of Analysis). Due to its niche status, availability may be limited; lead times can vary. Pricing is influenced by purity and scale, with bulk purchases (100g+) potentially reducing costs by 10–20%. Consider suppliers specializing in plant-derived bioactive compounds or TCM ingredients. For international procurement, verify compliance with regional regulations (e.g., REACH, USP).