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2,5-Hexanedione

Updated: 2026-07-15

Overview

2,5-Hexanedione, also known as acetonyl acetone, is a diketone with the molecular formula C6H10O2. It is a colorless to pale yellow liquid with a distinctive odor. The compound is widely used in industrial applications due to its solvent properties and role as a chemical intermediate. In the chemical industry, 2,5-hexanedione is valued for its versatility. It serves as a building block in organic synthesis, particularly in the production of pharmaceuticals, agrochemicals, and fragrances. Its ability to dissolve a wide range of substances makes it a useful solvent in various formulations.

Physical and Chemical Properties

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2,5-Hexanedione exhibits several notable physical and chemical properties. It has a boiling point of 191°C and a melting point of -7°C, making it a liquid at room temperature. The compound is soluble in water, alcohol, and ether, which enhances its utility as a solvent. Chemically, 2,5-hexanedione is reactive, particularly with strong oxidizing agents. It is also flammable, requiring careful handling and storage. The compound's volatility necessitates proper ventilation in areas where it is used or stored to prevent the accumulation of vapors.

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Main Applications

The primary applications of 2,5-hexanedione are in the chemical and pharmaceutical industries. As a solvent, it is used in the formulation of coatings, adhesives, and cleaning agents. Its role as an intermediate is crucial in the synthesis of various organic compounds. In the pharmaceutical sector, 2,5-hexanedione is employed in the production of active pharmaceutical ingredients (APIs). It is also used in the fragrance industry to create synthetic aromas. Additionally, the compound finds applications in agrochemicals, where it serves as a precursor in the synthesis of pesticides and herbicides.

Safety and Storage

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Handling 2,5-hexanedione requires strict adherence to safety protocols. The compound is harmful if swallowed or inhaled and can cause skin and eye irritation. Personal protective equipment (PPE) such as gloves, goggles, and respirators should be used when working with this chemical. Storage conditions are critical to maintaining the stability of 2,5-hexanedione. It should be kept in a cool, dry, well-ventilated area away from sources of ignition. Containers must be tightly sealed to prevent leaks and evaporation. Compatibility with storage materials should also be verified to avoid reactions with container surfaces.

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B2B Procurement Guide

When procuring 2,5-hexanedione, B2B buyers should prioritize quality and safety. Suppliers must provide a material safety data sheet (MSDS) that details the compound's hazards, handling instructions, and emergency measures. Buyers should also verify the purity and concentration of the product to ensure it meets their specific requirements. Price negotiation is another key consideration. The cost of 2,5-hexanedione can vary based on purity, quantity, and supplier. Bulk purchases often attract discounts, but buyers should balance cost savings with the need for reliable and consistent quality. Establishing long-term relationships with reputable suppliers can ensure a steady supply chain.

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