Overview
2,4,5-Trihydroxybenzaldehyde is an organic compound with the molecular formula C7H6O4. It is a derivative of benzaldehyde with hydroxyl groups at the 2, 4, and 5 positions. This compound is primarily used as an intermediate in pharmaceutical synthesis and dye production. Its structure makes it a valuable building block in organic chemistry. Due to its reactive aldehyde and hydroxyl groups, 2,4,5-Trihydroxybenzaldehyde can undergo various chemical reactions, including oxidation, reduction, and condensation. This versatility enhances its utility in industrial applications. The compound is typically supplied as a crystalline powder with varying degrees of purity.
Physical and Chemical Properties
2,4,5-Trihydroxybenzaldehyde is a light yellow to brown crystalline solid with a melting point of approximately 180-185°C. It is soluble in polar organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO), but only slightly soluble in water. The compound exhibits stability under normal storage conditions but may degrade upon prolonged exposure to light or moisture. The presence of multiple hydroxyl groups and an aldehyde functional group contributes to its reactivity. These functional groups make it susceptible to oxidation and other chemical transformations. The compound's molecular weight is 154.12 g/mol, and its density is not well-documented in available literature.
Main Applications
2,4,5-Trihydroxybenzaldehyde is widely used as an intermediate in the synthesis of pharmaceuticals, particularly in the production of drugs with phenolic structures. Its reactivity allows for the formation of complex molecules, making it valuable in medicinal chemistry. In addition to pharmaceuticals, the compound is employed in the synthesis of dyes and pigments. Its ability to form colored complexes with metals and other organic compounds makes it useful in the dye industry. It is also utilized in organic synthesis for the preparation of various aldehydes and phenolic derivatives.
Safety and Storage
Handling 2,4,5-Trihydroxybenzaldehyde requires caution due to its potential health hazards. Avoid inhalation, ingestion, or skin contact. Use personal protective equipment, including gloves and goggles, and work in a well-ventilated area. Store the compound in a cool, dry place away from light and moisture to maintain its stability. Proper storage conditions help prevent degradation and ensure the compound remains effective for its intended applications. Always refer to the material safety data sheet (MSDS) for detailed safety guidelines.
B2B Procurement Guide
When procuring 2,4,5-Trihydroxybenzaldehyde, prioritize suppliers with a proven track record of reliability and quality. Request certificates of analysis (CoA) to verify the compound's purity and ensure it meets your specifications. The reference price range is approximately $50-$200 per gram, depending on purity and supplier. Consider bulk purchasing for cost savings, but ensure proper storage facilities are available. Always review the MSDS and handle the compound according to safety protocols to mitigate risks during transportation and use.
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