Overview
2,4-Dinitrophenol (DNP) is an organic compound with the formula C6H4N2O5. It is a yellow crystalline solid primarily used in industrial applications. Historically, it was used as a weight-loss agent due to its metabolic effects, but this use has been banned due to severe toxicity risks. DNP is synthesized through the nitration of phenol and is known for its role in uncoupling oxidative phosphorylation in mitochondria. This property makes it valuable in biochemical research but hazardous in uncontrolled environments.
Physical and Chemical Properties
DNP exhibits a bright yellow color and sublimes upon heating. It has a density of 1.683 g/cm³ and a melting point between 108-112°C. The compound is soluble in organic solvents like ethanol and ether but only slightly soluble in water. Key chemical properties include its ability to uncouple oxidative phosphorylation, leading to increased metabolic rate and heat production. This makes it highly toxic, as it disrupts cellular energy production. DNP is also sensitive to shock and friction, posing explosion risks.
Main Applications
DNP is primarily used in the production of dyes, explosives, and pesticides. Its bright yellow color makes it useful as a dye intermediate. In explosives, it serves as a precursor due to its nitro groups. In biochemical research, DNP is used to study mitochondrial function and energy metabolism. However, its use in humans or animals is strictly prohibited due to its lethal effects. Industrial applications require strict safety protocols to prevent accidental exposure.
Safety and Storage
DNP is classified as highly toxic and requires stringent handling procedures. Exposure can occur through ingestion, inhalation, or skin contact, leading to severe hyperthermia and organ failure. Storage must be in a cool, dry, well-ventilated area, away from oxidizing agents. Personal protective equipment (PPE) such as gloves, goggles, and respirators is mandatory during handling. Spills should be contained and cleaned by trained personnel using appropriate absorbents.
B2B Procurement Guide
When procuring DNP, verify supplier credentials and ensure compliance with local and international regulations. Due to its hazardous nature, transportation and storage require specialized containers and documentation. Buyers should request material safety data sheets (MSDS) and certificates of analysis (CoA) to confirm purity and handling instructions. Bulk purchases may require additional permits or safety audits. Always prioritize suppliers with a proven track record in handling hazardous chemicals.
Related Manufacturers
- 主营：阻燃剂、催化剂、水杨酸、二苯基、乙二胺、酰亚胺、正磷酸、烟酰胺、曲酸粉、氯化锌、异丙醇、化妆品、初油酸、脂肪醇、生石灰、甲基异、碳酸锌、碳酸锂、活性炭、三氮唑、着色剂、环己酮、防冻液、抗氧剂、亚磷酸
- 主营：阻燃剂、乙酸镍、乙酸镝、庚二酸、硫酸锂、硫酸锶、溴氨酸、香茅醇、肌氨酸、锂电池、四氢萘、磷酸铬、碳酸镁、碳酸镍、防冻剂、磷酸铝、叔丁醇、氟苯基、浮选剂、稀释剂、羟乙基、去除剂、除磷剂、十八烯、蛋白酶
- 主营：环戊酮、甲酸镍、阻燃剂、二硝基苯酚、草酸镧、钼酸铵、催化剂、钒酸铋、溴氨酸、硝酸锆、碳酸镧、白僵菌、磷酸铁、钨酸酐、氟化镧、视黄醇、叔丁醇、杀螨剂、杀虫剂、醋酸钬、抗粘剂、氟化镥、肟菌酯、氢化钠、氯铂酸、氟化镁
- 主营：网站建设、企业官网设计、网站搭建
- 主营：化工中间体、食品添加剂、化工原料
- 主营：杂环化合物、丙烯酸系列
- 主营：硫酰胺、抗氧剂、氟苯基、2-戊酮酸、2-甲基丁酸、2-甲基丁酯、2-氰基嘧啶、对氰基苯酚、中间体、溴咪唑并、焦谷氨醇、异丁酰胺、利伐沙班、l-脯氨酰胺、l-苯基乳酸、l-氨基丙醇、d-苯基乳酸、3-氨基丙醇、邻氟苯甲酸、邻溴苯乙酸、间溴苯甲酸、丁位癸内酯
- 主营：碘甲苯、阻燃剂、碘丙烷、溴苯酚、3.4-二氟、2-丙二醇、cas627-30-5、cas831-82-3、碘丁烷、溴苯胺、碘癸烷、苯乙酮、碘苯胺、碘乙烷、苯甲酸、苯甲腈、cas766-85-8、1-碘辛烷、1-碘己烷、cas107-05-1、cas585-79-5、cas150-19-6、ab黑白料、苯甲酰胺、聚碳酸酯
- 主营：对照品、标准品、当归酸酐、728、佛手柑内酯、新当归内酯、补骨脂甲素、补骨脂乙素、羟基芍药苷、阿魏酸松柏酯、水合氧化前胡素、豆甾醇葡萄糖苷
- 主营：蒸馏水、50%双氧水、柠檬酸钠、二甲基亚砜、丙二醇丙醚、己二酸、二甲基甲酰胺、二甲基乙酰胺、精间苯二甲酸、N-甲基吡咯烷酮、呋喃、纯碱、片碱、冰醋酸、磷酸、正丁醇、异丙醇、甘油、四氯呋喃、环氧氯丙烷
- 主营：硫酸钡、覆盆子酮、胍基丙酸、二肌酸苹果酸、苯基膦酰二氯、二肌酸柠檬酸、早强防冻剂、食品级磷酸镁、食品级硫酸镁
- 主营：正辛胺、柠檬酸、尿嘧啶、119736-16-2、4-嘧啶酮、923289-21-8、152628-02-9、氨基二环、2346620-55-9、抗皱素、绿原酸、异丁基、三辛胺、双醚芴、姜黄素、角鲨烯、精磺胺、蒜氨酸、九甘醇、氟苯基、15397-15-6、苯甲酰胺、比卡鲁胺、四氢嘧啶、麦角硫因
- 主营：聚维酮碘、柠檬酸钴、溴化镍、磺酸二钠盐、间溴硝基苯、己二酰氯、氟化锌、焦锑酸钾、硫化钡、苯磺酰氯
- 主营：冰乙酸、环己酮、氯化亚砜、苯酚、二甲基亚砜、己二酸、乙二醇、二甲苯、四氢呋喃、三乙醇胺、甲基叔丁基醚、醋酸乙酯、异戊醇、环己烷、苯乙烯、正丁醇
- 主营：乙醛酸、铁甲酸、羟乙基、二甲基、邻苯二甲、2-羟基喹喔啉、2-苯并唑啉酮、3-环戊二羧酸、6-二氯异烟酸、2-氨基-5-氯苯酚、草酰胺、3-氯丙炔、苯甲酰胺、溴氯海因、3-氯水扬酸、磷酸三甲酯、对羟基苯海因