Overview
Suberone, also known as cycloheptanone, is a seven-membered cyclic ketone with the molecular formula C7H12O. It is a versatile chemical intermediate used in organic synthesis and industrial applications. Its cyclic structure and reactivity make it valuable for producing fragrances, pharmaceuticals, and specialty chemicals. First synthesized in the early 20th century, suberone is now produced through catalytic oxidation or other synthetic routes. Its significance lies in its role as a building block for complex molecules, particularly in the fragrance industry, where it contributes to musky and woody notes.
Physical and Chemical Properties
Suberone is a colorless to pale yellow liquid with a distinctive, slightly pungent odor. It has a density of 0.914 g/cm³ at 20°C and boils at 179-181°C. The compound is slightly soluble in water but miscible with common organic solvents like ethanol and ether. Chemically, suberone exhibits typical ketone reactivity, including nucleophilic addition and condensation reactions. Its seven-membered ring structure imparts moderate stability, though it can undergo ring-opening under certain conditions. The compound is flammable, with a flash point of 62°C, requiring careful handling to avoid ignition hazards.
Main Applications
Suberone is primarily used in organic synthesis as a precursor for fragrances, pharmaceuticals, and agrochemicals. In the fragrance industry, it serves as an intermediate for musk compounds and woody aroma chemicals. Its cyclic structure is also leveraged in pharmaceutical synthesis, particularly for bioactive molecules with seven-membered rings. Additionally, suberone finds niche applications in polymer chemistry and as a solvent for specialty coatings. Its volatility and solubility properties make it suitable for formulations requiring controlled evaporation rates. Industrial buyers often procure it for custom synthesis projects or as a reagent in multi-step chemical processes.
Safety and Storage
As a flammable liquid, suberone requires strict safety measures. It should be stored in tightly sealed containers away from heat, sparks, and open flames. Storage areas must be well-ventilated, and grounding is recommended to prevent static discharge. Personal protective equipment (PPE), including gloves and goggles, is essential when handling suberone. Inhalation or skin contact can cause irritation, so fume hoods or respirators are advised for large-scale operations. Spills should be contained with inert absorbents and disposed of as hazardous waste. Regulatory guidelines (e.g., OSHA, GHS) classify it as a Category 3 flammable liquid.
B2B Procurement Guide
When procuring suberone, B2B buyers should prioritize suppliers with certifications like ISO or GMP, especially for pharmaceutical-grade material. Key specifications to verify include purity (typically 98-99%), water content, and residual solvents. Bulk pricing varies based on quantity and grade, with industrial-grade commonly priced at $50-$100 per kg. Lead times may apply for custom synthesis orders. Buyers should also confirm logistics options, as suberone falls under hazardous material transport regulations. Long-term contracts with suppliers can stabilize costs and ensure consistent quality for recurring needs.
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