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2,3-Hexanedione

Updated: 2026-07-25

Overview

2,3-Hexanedione is an organic compound classified as a diketone, featuring two carbonyl groups at the 2nd and 3rd positions of a six-carbon chain. It is widely recognized for its role in the flavor and fragrance industries due to its buttery, caramel-like aroma. The compound is synthesized through controlled oxidation or other organic reactions, ensuring high purity for industrial applications. In addition to its sensory properties, 2,3-Hexanedione serves as a versatile intermediate in chemical synthesis, contributing to the production of pharmaceuticals, agrochemicals, and specialty chemicals. Its reactivity and stability make it a valuable component in various formulations.

Physical and Chemical Properties

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2,3-Hexanedione is a colorless to pale yellow liquid with a characteristic pungent odor. It has a molecular weight of 114.14 g/mol and a density of approximately 0.92 g/cm³. The compound boils at 139-141 °C and is soluble in most organic solvents, though it has limited solubility in water. Key chemical properties include its volatility and flammability, necessitating careful handling. The diketone structure makes it reactive, particularly in condensation and reduction reactions. These attributes are critical for its applications in synthetic chemistry and flavor enhancement.

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Main Applications

The primary use of 2,3-Hexanedione is as a flavoring agent in the food industry, where it imparts a buttery or caramel note to products like baked goods, dairy, and confectionery. It is also employed in the fragrance industry to create complex scent profiles for perfumes and household products. Beyond sensory applications, the compound acts as a chemical intermediate in the synthesis of heterocyclic compounds, pharmaceuticals, and agrochemicals. Its ability to participate in diverse reactions makes it a staple in organic synthesis laboratories and industrial processes.

Safety and Storage

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2,3-Hexanedione requires strict safety measures due to its flammability and potential health hazards. It should be stored in a cool, dry place away from ignition sources, in containers that prevent vapor release. Proper ventilation is essential to avoid accumulation of vapors in confined spaces. Personal protective equipment (PPE), including gloves, goggles, and respirators, should be used when handling the compound. In case of spills, absorbent materials and neutralizers should be applied immediately, and contaminated areas must be ventilated thoroughly.

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B2B Procurement Guide

When procuring 2,3-Hexanedione, prioritize suppliers with certifications like ISO or GMP to ensure product quality and consistency. Request detailed technical data sheets (TDS) and certificates of analysis (CoA) to verify purity, which typically ranges from 95% to 99% for industrial use. Bulk purchases often attract discounts, but consider storage limitations and shelf life. Establish long-term relationships with reliable suppliers to secure stable pricing and availability. For international shipments, confirm compliance with regional regulations such as REACH or TSCA.

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