2,3-Dibromopropionamide

Updated: 2026-07-22

Overview

2,3-Dibromopropionamide (2,3-DBPA) is a brominated organic compound with the molecular formula C3H5Br2NO. It is primarily used as an intermediate in chemical synthesis, particularly in the production of flame retardants and pharmaceuticals. The compound is known for its reactivity, making it valuable in various industrial processes. As a specialty chemical, 2,3-DBPA is typically supplied in crystalline powder form. Its synthesis involves bromination of propionamide derivatives, and it is handled with care due to its potential irritant properties. The compound’s applications are niche but significant in industries requiring brominated intermediates.

Physical and Chemical Properties

2,3-Dibromopropionamide appears as a white to off-white crystalline powder with a melting point of approximately 100-105°C. It is soluble in common organic solvents such as ethanol and acetone but exhibits limited solubility in water. The molecular weight is 230.88 g/mol, and its structure features two bromine atoms attached to a propionamide backbone. The compound’s reactivity stems from the presence of bromine atoms, which participate in substitution and elimination reactions. This makes it useful as a building block in synthetic chemistry. Stability under normal storage conditions is adequate, but exposure to moisture or extreme temperatures should be avoided.

Main Applications

2,3-Dibromopropionamide is primarily employed as a chemical intermediate in the synthesis of flame retardants, where brominated compounds are valued for their efficacy in reducing flammability. It is also used in pharmaceutical research for the preparation of brominated analogs of bioactive molecules. In addition, 2,3-DBPA finds use in agrochemicals and specialty polymers. Its role as a reactive intermediate allows for the introduction of bromine into target molecules, enabling further functionalization. The compound’s applications are largely industrial, with limited direct consumer use.

Safety and Storage

2,3-Dibromopropionamide is classified as an irritant, posing risks to skin and eyes upon contact. Proper handling requires the use of personal protective equipment (PPE), including gloves and safety goggles. Inhalation of dust should be avoided, and work should be conducted in a well-ventilated area. Storage recommendations include keeping the compound in a cool, dry place, away from direct sunlight and moisture. Containers should be tightly sealed to prevent degradation. In case of spills, absorb with inert material and dispose of according to local regulations.

B2B Procurement Guide

When procuring 2,3-Dibromopropionamide, buyers should prioritize suppliers with verified CAS numbers (3252-43-5) and certificates of analysis (CoA) to ensure purity and quality. Bulk purchases may offer cost advantages, but storage capacity and shelf life should be considered. Key procurement considerations include supplier reliability, compliance with safety regulations, and packaging options. Prices vary based on quantity and supplier, with a reference range of approximately $50-$100 per kilogram. Buyers are advised to request samples for quality testing before large-scale orders.