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2-Phenylpropionic Acid

Updated: 2026-07-15

Overview

2-Phenylpropionic acid, also known as hydratropic acid, is an organic compound with the molecular formula C9H10O2. It is a white to off-white crystalline powder with a mild aromatic odor. This compound is commonly used as an intermediate in pharmaceutical synthesis and fragrance production. The chemical is structurally related to phenylacetic acid but features an additional methyl group, which influences its reactivity and solubility. Its aromatic nature makes it useful in various organic synthesis applications.

Physical and Chemical Properties

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2-Phenylpropionic acid has a melting point of approximately 47-50°C and a boiling point of around 265-267°C. It is soluble in organic solvents like ethanol and ether but has limited solubility in water. The compound's weak acidity and aromatic structure make it suitable for specific chemical reactions. The density of 2-phenylpropionic acid is not widely documented, but its crystalline form suggests moderate stability under standard conditions. Its solubility profile and reactivity are key considerations for industrial applications.

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Main Applications

The primary use of 2-phenylpropionic acid is as an intermediate in pharmaceutical manufacturing. It serves as a building block for active pharmaceutical ingredients (APIs) and other drug components. Its aromatic properties also make it valuable in fragrance synthesis. Additionally, the compound is employed in organic synthesis for producing specialty chemicals. Its versatility in reactions involving carboxyl groups and aromatic rings expands its utility in research and industrial settings.

Safety and Storage

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2-Phenylpropionic acid is classified as an irritant to skin and eyes. Proper handling requires protective equipment such as gloves and goggles. Adequate ventilation is recommended to avoid inhalation of dust or vapors. Storage should be in a cool, dry place away from direct sunlight and incompatible materials. The compound is stable under normal conditions but may degrade if exposed to moisture or extreme temperatures for prolonged periods.

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B2B Procurement Guide

When procuring 2-phenylpropionic acid, verify the supplier's certifications and batch consistency. Purity levels (e.g., 98%, 99%) should align with your application requirements. Request material safety data sheets (MSDS) and certificates of analysis (CoA) for quality assurance. Bulk purchases may offer cost advantages, but storage capacity and shelf life should be considered. Compare prices from multiple suppliers, keeping in mind that higher purity grades typically command premium pricing.

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