Overview
2-Phenylethylamine (PEA) is an organic compound belonging to the class of aromatic amines. It is naturally occurring in trace amounts in the human brain and is also synthesized industrially for various applications. Industrial-grade PEA is primarily used in chemical synthesis, pharmaceuticals, and fragrance production. PEA is known for its role as a precursor in the synthesis of numerous bioactive compounds, including neurotransmitters and pharmaceuticals. Its versatility and reactivity make it a valuable intermediate in organic chemistry.
Physical and Chemical Properties
2-Phenylethylamine is a colorless to pale yellow liquid with a strong, amine-like odor. It has a molecular weight of 121.18 g/mol and a density of 0.96 g/cm³. The compound is soluble in water, alcohol, and ether, and it exhibits alkaline properties due to its amine group. PEA has a boiling point of 195-200°C and a melting point of -60°C. It is volatile and should be handled with care to avoid inhalation or skin contact. The compound's reactivity makes it useful in various chemical reactions, including alkylation and acylation.
Main Applications
2-Phenylethylamine is widely used in the pharmaceutical industry as an intermediate for the synthesis of drugs such as antidepressants, stimulants, and vasoconstrictors. It is also employed in the production of fragrances and flavorings due to its aromatic properties. In industrial settings, PEA serves as a building block for the synthesis of more complex organic compounds. Its applications extend to research laboratories, where it is used in biochemical studies and organic synthesis.
Safety and Storage
2-Phenylethylamine is corrosive and can cause irritation to the skin, eyes, and respiratory system. Proper personal protective equipment (PPE), including gloves, goggles, and lab coats, should be worn when handling the compound. A fume hood is recommended to minimize exposure to vapors. Storage should be in a cool, dry, well-ventilated area away from heat sources and open flames. The compound should be kept in tightly sealed containers to prevent moisture absorption and degradation.
B2B Procurement Guide
When procuring industrial-grade 2-phenylethylamine, it is essential to verify the CAS number (64-04-0) and the purity level required for your application. Suppliers should provide certificates of analysis (CoA) and material safety data sheets (MSDS). Bulk purchases often come with price discounts, so consider negotiating for larger quantities if your usage is consistent. Ensure that the supplier adheres to industry standards and regulations to guarantee product quality and safety.
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