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2-Phenylethanol

Updated: 2026-07-17

Overview

2-Phenylethanol is an aromatic alcohol with a characteristic rose-like scent, extensively utilized in fragrance and flavor industries. It occurs naturally in essential oils (e.g., rose, jasmine) but is primarily synthesized for commercial scale. Its versatility stems from its pleasant odor, solubility, and antimicrobial effects, making it indispensable in perfumes, soaps, and food additives. The compound is produced via Friedel-Crafts alkylation of benzene with ethylene oxide or through biotechnological routes using yeast. Regulatory bodies like IFRA and FDA approve its use in cosmetics and food, provided it meets purity standards.

Physical and Chemical Properties

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2-Phenylethanol is a colorless, slightly viscous liquid with a boiling point of 219-221°C and a density of 1.02 g/cm³. It exhibits moderate solubility in water but blends well with organic solvents like ethanol and glycerin. The compound is stable under ambient conditions but may oxidize over prolonged exposure to air. Its floral aroma is detectable at low concentrations (0.1-10 ppm), making it effective in trace formulations. The hydroxyl group enables hydrogen bonding, influencing its solubility and reactivity in formulations.

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Main Applications

In perfumery, 2-phenylethanol serves as a fixative and middle note in floral compositions (e.g., rose, lilac). It is a staple in soaps, lotions, and shampoos due to its stability in alkaline environments. The food industry employs it as a flavoring agent (e.g., honey, peach notes) in beverages and confectionery. Pharmaceutical applications include its use as a preservative in vaccines and topical antiseptics. Its antimicrobial properties (effective against bacteria like E. coli) also make it valuable in sanitizers.

Safety and Storage

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While generally safe, undiluted 2-phenylethanol can irritate skin and eyes. Proper PPE (gloves, goggles) is recommended during handling. Storage requires airtight containers in cool (<25°C), dark environments to prevent oxidation. Incompatible with strong oxidizers (e.g., peroxides). Regulatory limits include IFRA’s maximum dermal use level of 1.0% in leave-on products. SDS documentation must accompany shipments, detailing first-aid measures (rinse with water if exposed).

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B2B Procurement Guide

Bulk buyers should prioritize suppliers with ISO 9001 or GMP certification to ensure consistency. Key specifications include purity (≥99%), water content (<0.1%), and absence of heavy metals. Request COA (Certificate of Analysis) for each batch. Logistics considerations: Opt for HDPE drums or IBC totes for shipments. Spot-market prices fluctuate with benzene feedstock costs; long-term contracts may offer stability. Sample testing for odor profile and solubility is advised before large orders.

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