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2-Pentanediol

Updated: 2026-07-31

Overview

2-Pentanediol, also known as 1,2-pentanediol, is a diol compound with the molecular formula C5H12O2. It is a colorless, hygroscopic liquid with a mild odor. This compound is widely used in various industries due to its solvent properties and low toxicity. Its versatility makes it a valuable ingredient in pharmaceuticals, cosmetics, and industrial applications. 2-Pentanediol is synthesized through the hydration of pentene or via other chemical processes. It is known for its ability to dissolve a wide range of substances, making it a preferred choice in formulations requiring a stable and effective solvent.

Physical and Chemical Properties

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2-Pentanediol has a molecular weight of 104.15 g/mol and a density of 0.962 g/cm³. It is soluble in water and most organic solvents, which enhances its utility in various applications. The compound has a boiling point of 206°C, making it stable under typical processing conditions. Its hygroscopic nature means it can absorb moisture from the environment, which is a consideration for storage and handling. The low toxicity of 2-pentanediol makes it safer to handle compared to many other industrial solvents, though proper safety measures should still be observed.

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Main Applications

In the pharmaceutical industry, 2-pentanediol is used as a solvent and excipient in drug formulations. Its ability to enhance the solubility of active pharmaceutical ingredients (APIs) makes it a valuable component in topical and oral medications. The cosmetics industry utilizes 2-pentanediol in skincare products, where it acts as a humectant and solvent. It helps to maintain moisture and improve the texture of creams and lotions. Additionally, its antimicrobial properties contribute to product preservation.

Safety and Storage

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2-Pentanediol is generally considered safe when handled properly, but it can cause irritation upon contact with skin or eyes. Personal protective equipment, such as gloves and goggles, should be worn when handling the chemical. Storage should be in a cool, dry, well-ventilated area, away from heat sources and open flames. Containers should be tightly sealed to prevent moisture absorption and contamination. Proper labeling and adherence to safety regulations are essential for safe storage and use.

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B2B Procurement Guide

When procuring 2-pentanediol, buyers should prioritize suppliers with certifications such as ISO or GMP, ensuring product quality and consistency. It is advisable to request detailed specifications, including purity levels and potential impurities. Bulk purchases often result in cost savings, but buyers should assess their storage capabilities to avoid degradation. Establishing long-term relationships with reliable suppliers can ensure steady supply and favorable terms. Additionally, buyers should stay informed about market trends and regulatory changes affecting the availability and pricing of 2-pentanediol.

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