Overview
2-Oxazolidinone is a five-membered heterocyclic compound containing both nitrogen and oxygen atoms. It serves as a key intermediate in the synthesis of various pharmaceuticals, including antibiotics and antifungal agents. The compound is also utilized in agrochemicals and polymer production due to its reactivity and stability. Its versatility in chemical reactions makes it a valuable building block in organic synthesis. The demand for 2-oxazolidinone has grown significantly in recent years, driven by advancements in pharmaceutical research and industrial applications.
Physical and Chemical Properties
2-Oxazolidinone is a white crystalline solid with a molecular weight of 87.07 g/mol. It has a density of 1.32 g/cm³ and a melting point range of 89-91°C. The compound is soluble in water, ethanol, and acetone, making it suitable for various solvent-based reactions. It is stable under normal conditions and non-flammable, but it should be handled with care to avoid inhalation or skin contact. The compound's reactivity is primarily due to the presence of the carbonyl group and the nitrogen atom in the ring structure.
Main Applications
2-Oxazolidinone is predominantly used as an intermediate in the pharmaceutical industry. It is a precursor for the synthesis of antibiotics such as linezolid and other oxazolidinone-based drugs. These antibiotics are effective against Gram-positive bacteria, including resistant strains like MRSA. In addition to pharmaceuticals, 2-oxazolidinone finds applications in agrochemicals, where it is used to produce pesticides and herbicides. The compound is also employed in polymer synthesis, contributing to the development of specialty polymers with unique properties.
Safety and Storage
2-Oxazolidinone should be stored in a cool, dry place away from moisture and direct sunlight to maintain its stability. Proper ventilation is recommended when handling the compound to prevent inhalation of dust or vapors. Personal protective equipment, such as gloves and safety goggles, should be worn to minimize skin and eye contact. In case of exposure, rinse thoroughly with water and seek medical advice if necessary. The compound is not classified as highly hazardous, but prudent handling practices are essential.
B2B Procurement Guide
When procuring 2-oxazolidinone, B2B buyers should prioritize suppliers with verified certifications and a track record of consistent quality. Purity levels, typically ranging from 98% to 99.5%, should be confirmed through certificates of analysis. Bulk purchases often come with price advantages, but buyers should also consider storage capacity and shelf life. It is advisable to request samples for testing before committing to large orders. Additionally, inquire about packaging options to ensure safe transportation and storage.
Related Manufacturers
- 主营：二异丁基酮、异戊酮、二氯二乙醚、环氧丙烷、3-溴-4-氟苯甲腈、2-戊酮酸 2-氧代、苄硫醇 α-甲苯硫醇、乙醇酸钠、十氢萘、六甲基磷酰三胺、巯基乙酸、硫代乙酸、四聚丙烯 十二烯、对氯三氟甲苯、环戊甲酸、氯磺酸、氯代叔丁烷 叔丁基氯、甲硫醇、二甲基一氯硅烷、三氟氯乙烯、一甲基三氯硅烷
- 主营：胶囊破胶剂、过硫酸铵、过硫酸钠、过硫酸钾、淀粉、乙二醇、乙酸钠、异丙醇、苯乙烯、石油化工、助剂原料
- 主营：二甘醇、三甘醇、四甘醇、1.3-丙二醇、丙二醇、二丙二醇、异己二醇、乙二醇丁醚、二乙二醇丁醚、三乙二醇丁醚、丙二醇甲醚、二丙二醇甲醚、丙二醇丁醚、二丙二醇丁醚、三醋酸甘油酯、乙二醇、甘油、正庚烷、异丙醇、异辛醇、一乙醇胺、二乙醇胺、三乙醇胺、太古油40%/60%、分散剂NNO系列
- 主营：氯乙酰、脱漆剂、柠檬酸、乙氧基乙醇、二甲苯、塔尔油、正庚烷、三甘醇、乳化剂、催化剂、正丙醇、减水剂、丙三醇、除臭剂、渗透剂、防水剂、石油醚、润滑油、黄糊精、硫酸钾、羊毛脂、洗发水、白矿油、保水剂、蜗牛敌、清漆剂
- 主营：磷酸三甲苯酯、氨基甲酸乙酯、磷酸甲苯二苯酯、甲乙酮肟、四乙基溴化铵、碳酸二丁酯、环烷酸铅、亚硫酸铵、二苯甲酮腙、石油磺酸钠、三乙醇胺、甲醇、乙醇、二甲苯、二氯甲烷、环烷酸铜、氨基甲酸甲酯、单过硫酸氢钾、氯化石蜡、三异丙醇胺、苄基三甲基氯化铵、苄基三乙基氯化铵、四乙基氯化铵、四甲基氯化铵、新癸酸铋
- 主营：十六烷基三甲基溴化铵、十二烷基甜菜咸、乳化剂、氧代丙酸乙酯、亚磷酸三丁酯、棕榈油、钛酸四丁酯、钛酸四乙酯
- 主营：聚乙烯亚胺、三甘醇二异辛酸酯3G8、三硫代碳酸钠40%、TS-1钛硅分子筛、5-甲基靛红、六氯环三磷腈、烷基苯磺酸酯、苯基次磷酸钠、甲巯咪唑、吡啶硫酮锌、焦磷酸哌嗪、热敏材料、油酸甲酯、曲酸
- 主营：三硫代碳酸钠、聚乙烯亚胺、三乙二醇二异辛酸酯、红色素-16、L-丙交酯、石油酯-T50、巯基苯并噻唑钠、乙交酯、多元醇苯甲酸酯、热压敏染料、光稳定剂、高分子降解材料
- 主营：有机原料、中间体、香精香料、氧代己酸、催化剂、有机硅、表面活性剂
- 主营：叔碳酸、十八醛、溶菌酶、2-甲基丁醛、10-羟基羊蜡酸、海藻糖、癸二醇、氨基丙基、氢路噻嗪、邻苯二甲、乙基碳二、羟基癸酸、正十七烷、谷胱甘肽、烷二甲醇、松果体素、vc磷酸酯镁、朱栾倍半萜、丁烷四乙酸、表面活性剂、癸烷撑二醇、缩水甘油邻、氢氯噻嗪杂质、盐酸邻菲罗啉、壳聚糖季铵盐
- 主营：化学品、香精香料、试剂、氧代戊二酸alpha、中间体、有机硅、橡胶树脂、催化剂、纳米材料
- 主营：丙烯酸单体、全氟三丁胺、甲基丙烯酸十八酯、环氧稀释剂、乙二醇二缩水甘油醚、催化剂、催干剂、增塑剂、偶联剂、交联剂、橡胶塑料助剂、电镀电子科技材料、丙烯酸酯类
- 主营：异辛醇、乳化剂、乙烯醚、聚氧乙烯、甲酯乙氧基、醚羧酸、脂肪醇、分散剂、染色助剂、聚乙二醇、异构醇醚、泊洛沙姆、椰油酰胺、基羟乙基、烷基糖苷、特辛基酚、嵌段聚醚、单油酸酯、异构十三醇、丙烯磺酸钠、氢化蓖麻油、丙烯酰胺基、醇醚葡糖苷、低泡渗透剂、癸基葡糖苷
- 主营：硬脂酸、正己醇、植物油酸、二乙酰氧基、异佛尔酮、碳酸二苯酯
- 主营：标准溶液、标准滴定溶液、Ph缓冲溶液、氧代戊二酸缓冲液、电导率校正液、中国药典试液