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2-Methyltryptamine

Updated: 2026-08-03

Overview

2-Methyltryptamine (2-MT) is a synthetic compound belonging to the tryptamine class, which includes substances like serotonin and melatonin. It is structurally similar to these naturally occurring compounds but features a methyl group at the alpha position of the ethylamine side chain. This modification alters its pharmacological properties, making it a subject of interest in research settings. While 2-MT is not widely used in commercial applications, it has been studied for its potential psychoactive effects. Its role as a research chemical underscores the importance of understanding its properties and handling it with care in laboratory environments.

Physical and Chemical Properties

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2-Methyltryptamine is a white to off-white crystalline powder with a molecular weight of 174.24 g/mol. It has a melting point of approximately 140-142°C, which is characteristic of many tryptamine derivatives. The compound is soluble in organic solvents like ethanol and methanol but exhibits limited solubility in water. Its chemical structure includes an indole ring system, which is common among tryptamines. The addition of a methyl group at the alpha position affects its binding affinity to serotonin receptors, contributing to its psychoactive potential. These properties make it a compound of interest in pharmacological research.

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Main Applications

The primary application of 2-Methyltryptamine is in research settings, where it is used to study the effects of tryptamine derivatives on the central nervous system. Its structural similarity to serotonin allows researchers to explore its interactions with serotonin receptors, providing insights into neurotransmitter systems. In addition to its role in neuroscience research, 2-MT has been investigated as a potential intermediate in the synthesis of more complex pharmaceutical compounds. However, its use in commercial pharmaceuticals remains limited due to regulatory and safety considerations.

Safety and Storage

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2-Methyltryptamine should be handled with caution due to its psychoactive properties. Appropriate personal protective equipment (PPE), including gloves and lab coats, should be worn when working with this compound. It is also advisable to work in a well-ventilated area to minimize exposure. Storage conditions are critical to maintaining the stability of 2-MT. The compound should be kept in a cool, dry place away from light and moisture. Proper labeling and secure storage are essential to prevent accidental ingestion or misuse.

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B2B Procurement Guide

When procuring 2-Methyltryptamine for research purposes, it is essential to verify the credentials of suppliers. Look for vendors who provide certificates of analysis (CoA) to ensure product purity and compliance with regulatory standards. Pricing can vary significantly based on quantity and supplier, so obtaining multiple quotes is advisable. Due to the compound's psychoactive nature, buyers should ensure that their procurement activities comply with local and international regulations. This includes obtaining necessary permits and documenting the intended use of the compound. Transparency and due diligence are key to responsible procurement.

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