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2-Methylpropionamide

Updated: 2026-08-06

Overview

2-Methylpropionamide, also known as isobutyramide, is an organic compound with the molecular formula C4H9NO. It is a derivative of isobutyric acid and is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. The compound is known for its stability and solubility in common organic solvents, making it a versatile reagent in industrial applications. Due to its role in chemical synthesis, 2-methylpropionamide is often procured by B2B buyers in bulk quantities. Its relatively simple structure and functional group make it a valuable building block for more complex molecules. The compound is typically supplied as a white crystalline solid, ensuring ease of handling and storage.

Physical and Chemical Properties

兴琰 3-(N-甲基正戊胺基)丙酸盐酸盐 中间体 625120-81-2湖北兴琰新材料科技有限公司

2-Methylpropionamide is a white crystalline solid with a melting point of approximately 125-127°C. It is soluble in water, ethanol, and ether, which enhances its utility in various chemical reactions. The compound is stable under normal conditions and is non-flammable, reducing risks associated with storage and transportation. The molecular weight of 2-methylpropionamide is 87.12 g/mol, and its structure includes an amide functional group, which is key to its reactivity. This functional group allows it to participate in condensation reactions and other synthetic pathways, making it a valuable intermediate in organic chemistry.

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Main Applications

2-Methylpropionamide is primarily used as an intermediate in the pharmaceutical industry, where it contributes to the synthesis of active pharmaceutical ingredients (APIs). Its role in agrochemical production is also significant, as it serves as a precursor for herbicides and pesticides. In addition to pharmaceuticals and agrochemicals, 2-methylpropionamide finds applications in the production of specialty chemicals, including dyes, resins, and coatings. Its versatility and reactivity make it a preferred choice for manufacturers seeking reliable and efficient chemical intermediates.

Safety and Storage

3-(N-甲基正戊胺基)丙酸盐酸盐 有机中间体 625120-81-2江苏润丰合成科技有限公司

While 2-methylpropionamide is generally stable, it is important to handle it with care to avoid potential health hazards. Direct contact with skin or eyes should be avoided, and protective equipment such as gloves and goggles should be used during handling. Storage conditions should be cool, dry, and well-ventilated, away from direct sunlight and moisture. Proper labeling and containment are essential to prevent accidental exposure. In case of spillage, the area should be cleaned immediately using appropriate absorbent materials.

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B2B Procurement Guide

When procuring 2-methylpropionamide, B2B buyers should prioritize suppliers with verified certifications and a track record of reliability. Key considerations include the compound's purity, which should meet the specific requirements of the intended application. Price ranges for 2-methylpropionamide vary depending on purity and supplier, with typical costs ranging from $50 to $100 per kilogram. Bulk purchases may offer cost advantages, but buyers should ensure that storage facilities are adequate to maintain the compound's integrity over time.

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