Overview
2-Methylbutyric Anhydride is an organic compound derived from 2-methylbutyric acid. It is widely used in the chemical industry for its acylating properties, making it valuable in the synthesis of esters, amides, and other derivatives. The compound is particularly significant in the production of flavoring agents and pharmaceutical intermediates. Due to its reactive nature, 2-Methylbutyric Anhydride must be handled with care. It is typically supplied in sealed containers to prevent moisture absorption, which can lead to hydrolysis and reduced efficacy.
Physical and Chemical Properties
2-Methylbutyric Anhydride is a colorless to pale yellow liquid with a characteristic odor. It has a molecular weight of 186.25 g/mol and a density of approximately 0.95 g/cm³ at 20°C. The compound is soluble in common organic solvents such as ethanol and ether but only slightly soluble in water. Its boiling point ranges between 195-200°C, and it is highly reactive, especially in the presence of water or alcohols. The anhydride group makes it an effective acylating agent, suitable for various chemical transformations.
Main Applications
The primary use of 2-Methylbutyric Anhydride is in organic synthesis, where it serves as an acylating agent for the introduction of the 2-methylbutyryl group into other molecules. It is extensively used in the flavor and fragrance industry to produce esters that contribute to fruity and buttery notes. In pharmaceuticals, it acts as an intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its reactivity and specificity make it a preferred choice for controlled chemical reactions in laboratory and industrial settings.
Safety and Storage
2-Methylbutyric Anhydride is corrosive and can cause severe skin and eye irritation. Proper personal protective equipment (PPE), including gloves and goggles, is essential when handling this chemical. Work should be conducted in a well-ventilated area or under a fume hood to avoid inhalation of vapors. Storage conditions should be cool, dry, and away from heat sources or open flames. Containers must be tightly sealed to prevent moisture ingress, which can lead to decomposition. Spills should be neutralized with a suitable absorbent and disposed of according to local regulations.
B2B Procurement Guide
When procuring 2-Methylbutyric Anhydride, buyers should verify the CAS number (13730-91-7) to ensure product authenticity. Purity levels, typically ranging from 95% to 99%, should be confirmed based on intended use. Packaging options include glass bottles or metal drums, depending on quantity requirements. Supplier reliability is crucial; opt for vendors with proven track records in chemical distribution. Prices vary based on purity and order volume, with bulk purchases often attracting discounts. Always request safety data sheets (SDS) and certificates of analysis (CoA) for quality assurance.
Related Manufacturers
- 主营：四氢噻吩、乙酰氯、氢氟酸、二甲基亚砜、二甲基二硫醚、二甲基硫醚、二甲苯、甲酰胺、丙烯腈、正丙醇、水杨酸、甲酸钠、正丙醛、苯甲醛、丙二腈、硬脂酸、石油醚、水合肼、氯乙酸、乙二醛、乙二醇、异戊烷、苯乙烯、仲丁胺、叔丁醇
- 主营：四氢噻吩、一乙醇胺、异辛醇、二甲基二硫、二甲基亚砜、3-乙氧基丙胺、环丁砜、异丙醚、环己酮、异辛烷、氟硼酸、三乙胺、正庚烷、燕化苯酚、马来酸酐、三乙醇胺、亚硝酸钠、鲁西甲酸、三氧化二锑
- 主营：二甲基亚砜、乙二醇、丙二醇、DMAC
- 主营：花生酸、碳酸钠、单氟磷酸钠、丁基羟基茴香醚、鱼大豆酵母原料
- 主营：壬二酸、羟乙基、三胜肽、302776-68-7、玻色因、依克多因、抗坏血酸、谷胱甘肽、苯甲酸己酯、葡糖基芦丁、紫外吸收剂、辛氧基甘油、生物素三肽、乙酰基四肽、棕榈酰三肽、肉豆蔻酰五肽、植物油脂肪酸、氨基羟苯甲酰、紫外线吸收剂、维生素c乙基醚、二氢燕麦生物碱、苯乙基间苯二酚、水杨酸乙基己酯、乙基己基三嗪酮
- 主营：叔碳酸、十八醛、溶菌酶、2-甲基丁醛、10-羟基羊蜡酸、海藻糖、癸二醇、氨基丙基、氢路噻嗪、邻苯二甲、乙基碳二、羟基癸酸、正十七烷、谷胱甘肽、烷二甲醇、松果体素、vc磷酸酯镁、朱栾倍半萜、丁烷四乙酸、表面活性剂、癸烷撑二醇、缩水甘油邻、氢氯噻嗪杂质、盐酸邻菲罗啉、壳聚糖季铵盐
- 主营：抗氧剂BHT、苯磺酸、苯酚磺酸、N235 萃取剂、C272萃取剂、环烷酸铈、均苯四甲酸二酐、对苯乙烯磺酸钠、氟化铝、椰油酰胺丙基甜菜碱、甘油三苯甲酸酯
- 主营：乙醇钠、盐酸胍、对氯苯甲酸、甲基磺酸、四甲基乙二胺、丙酸乙酯、乙二醛、正丁醚、十二烷基苯、对二氯苯、硫醇、多聚磷酸、戊二醛、二氯甲烷、碳酸钾、双氰胺、偶氮二异丁腈、正己醇、乙腈、二氧六环、水杨醛、对甲酚、吗啉、咪唑
- 主营：乙二醇、丙二醇、精对苯二甲酸、二甲基亚砜、4-丁二醇、己二酸、聚乙烯醇、聚乙二醇、木质素、甘油、三甘醇、己内酰胺、叔十二硫醇、白油、对苯二甲酸二甲酯
- 主营：橡胶油、白芷油、pbtcaona4、7782-92-5、二甲基、2905-60-4、5989-81-1、1305-62-0、1192-62-7、9005-32-7、7775-27-1、8050-09-7、1739-84-0、7786-30-3、6920-22-5、1897-52-5、7727-21-1、艾叶油、桉树醇、重质苯、活性炭、安息油、正辛烷、黄糊精、三辛胺
- 主营：增塑剂、草酸镍、阻燃剂、1-二十烯、栀子蓝、抗氧剂、偶联剂、异壬酸、间氟溴苄、异胞嘧啶、磷酸三钾、油墨油剂、洗涤助剂、苯磺酸钠、单体香料、环磺酮酸、分散染料、无机颜料、苹果酸镁、表面处理剂、丙二醇甲醚、化妆品原料、丁酸甘油酯、硅烷处理剂、表面活性剂
- 主营：化学试剂、氯金酸、卡尔费休、异丁酸酐、乙醇、异丙醇、药用辅料、依地酸钙钠、碳酸钠、盐酸氨丁三醇、龙胆酸、枸橼酸钠、甲醇、氢氧化钠、钴锰催化剂、硫酸锰、乙腈、色谱试剂、助剂、指示剂、醋酸锰、醋酸钴、氨丁三醇、尿素、硼酸
- 主营：化工中间体、生物缓冲剂、实验试剂助剂
- 主营：生物缓冲剂、苯甲酸系列、农药、合成中间体
- 主营：米淀粉、催化剂、防水剂、异丁酸酐、精甲醇、氯丙烯、干基钒、灭火剂、碳酸镍、十二烷、清洗剂、酰化剂、异戊醇、氯化锌、软化剂、异丙醇、初油酸、氧化锌、杀菌剂、溴乙烷、乙二醛、氧化铅、固化剂、活性炭、甲酸钾、甲酸钠