2-Methoxy-4-methylaniline

Updated: 2026-07-31

Overview

2-Methoxy-4-methylaniline, also known as cresidine, is an aromatic amine primarily utilized as an intermediate in the synthesis of dyes and pigments. Its molecular structure includes a methoxy group and a methyl group attached to a benzene ring, contributing to its reactivity and solubility properties. The compound is commonly found in pale yellow to brown crystalline form and is known for its role in producing vibrant colorants for textiles and industrial applications. As a key chemical in the dye industry, 2-Methoxy-4-methylaniline is valued for its ability to form stable diazo compounds, which are essential for azo dye production. Its consistent performance and relatively low cost make it a preferred choice among manufacturers seeking reliable intermediates for synthetic dye processes.

Physical and Chemical Properties

2-Methoxy-4-methylaniline exhibits distinct physical and chemical characteristics that influence its industrial applications. With a molecular weight of 137.18 g/mol, it has a melting point range of 51-54°C and a boiling point of approximately 235°C. The compound's density is 1.08 g/cm³, and it is soluble in organic solvents like ethanol and ether while being only slightly soluble in water. Chemically, this compound is classified as an aromatic amine, featuring both electron-donating methoxy and methyl groups that enhance its reactivity in electrophilic substitution reactions. These properties make it particularly useful in diazotization reactions, where it serves as a precursor for azo dyes and other colorants. Its stability under normal storage conditions and compatibility with various industrial processes further contribute to its widespread use.

Main Applications

The primary application of 2-Methoxy-4-methylaniline lies in the dye and pigment industry, where it acts as a crucial intermediate for producing azo dyes. These dyes are widely used in textile coloring, printing inks, and plastics due to their bright hues and colorfastness. The compound's ability to form stable diazo compounds makes it indispensable in synthesizing complex dye molecules. Beyond dyes, this chemical finds use in pharmaceutical manufacturing as a building block for certain active ingredients. Its derivatives may also serve in agrochemical production, though this application is less common. The versatility of 2-Methoxy-4-methylaniline in organic synthesis continues to drive demand from specialty chemical manufacturers seeking efficient pathways to complex aromatic compounds.

Safety and Storage

Proper handling of 2-Methoxy-4-methylaniline requires strict adherence to safety protocols due to its classification as a harmful substance. The compound can cause skin and eye irritation upon contact and may be harmful if swallowed or inhaled. Appropriate personal protective equipment, including gloves, goggles, and respiratory protection, should be used when working with this chemical. Storage conditions are critical for maintaining the compound's stability. It should be kept in a cool, dry, well-ventilated area away from oxidizing agents and sources of ignition. Containers must be tightly sealed to prevent moisture absorption and contamination. In case of spillage, absorbent materials should be used for containment, followed by proper disposal according to local environmental regulations.

B2B Procurement Guide

When procuring 2-Methoxy-4-methylaniline for industrial use, several factors warrant careful consideration. Buyers should verify the CAS number (120-71-8) to ensure product authenticity and request certificates of analysis documenting purity levels, which typically range from 98% to 99% for industrial-grade material. Technical specifications should confirm the absence of undesirable impurities that might affect downstream applications. Supplier evaluation should include assessment of manufacturing capabilities, quality control processes, and compliance with relevant chemical regulations. Bulk purchases may offer cost advantages, but storage capacity and consumption rates should be balanced to prevent material degradation. Establishing long-term relationships with reputable suppliers can ensure consistent quality and reliable supply chains for this important chemical intermediate.